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首页> 美国政府科技报告 >Partnership Training Program: Studying Targeted Drug Delivery Using Nanoparticles in Breast Cancer Diagnosis and Therapy.
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Partnership Training Program: Studying Targeted Drug Delivery Using Nanoparticles in Breast Cancer Diagnosis and Therapy.

机译：伙伴关系培训计划：研究使用纳米粒子在乳腺癌诊断和治疗中的靶向药物传递。

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In the fourth year of this training grant, 11 faculty, 6 postdocs, 9 graduate and 1 undergraduate students from 7 departments at the Howard University have been trained in using nanoparticles as targeted drug delivery vehicles for cancer diagnosis and therapy. 25 seminars and workshops in cancer, molecular imaging, and nanomedicine have been offered. The trainees have received hands-on training in nanotechnology, MRI and optical imaging, cell biology lab techniques, and small animal handling. We implemented a new NMR method to measure kinetics of chemical exchange of ligand-target complex in solid tumor for pharmacokinetic modeling. We generated a humanized bivalent scFv-derived, DT390-based recombinant immunotoxin, which exhibited high cytotoxicity and anti-tumor efficacy against cancer cells. 16 research projects utilized the Nanomedicine Core. We published 7 research papers and review articles on nanotechnology in cancer research. Nanomedicine Core users have submitted 10 grant applications, and received two new NIH grants. The Core continued to be a synergy center drawing multidisciplinary research using nanotechnology for cancer research.

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