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Long Fiber Formation of Hydroxyapatite/Collagen Nanocomposites through a Self-Organization Mechanism

机译:通过自组织机制长纤维形成羟基磷灰石/胶原纳米复合材料

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摘要

Long fibers of bone-like hydroxyapatite/collagen nanocomposites were fabricated via a self-organization under biomimetic conditions to obtain much more suitable biomechanical and biochemical properties for artificial bone and tissue engineering scaffolds. The fiber growth was controlled with ionic strength in the reaction vessel and was explained by a crystal growth model. The composite fiber grew up to 75 mm in length and demonstrated straight extinction under a polarized microscope. The composite compacts were incorporated into bone metabolism, and their resorption was controlled with cross linkage. The composite is utilizable for the bone reconstruction materials that can gradually change into bone.

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