• 主题
高级搜索  >
历史搜索 清空历史
首页> 美国政府科技报告 >Label-Free and Chemical-Selective Microendoscope to Enhance Prostate Cancer Surgical Outcomes.
【24h】

Label-Free and Chemical-Selective Microendoscope to Enhance Prostate Cancer Surgical Outcomes.

机译：无标记和化学选择性微内窥镜，以增强前列腺癌手术结果。

获取原文
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Identification of cavernous nerves (CNs) and prostate surgical margins are two critical determinants for the outcome of radical prostatectomy. Currently there is no real time cancer diagnosis technology available when doing the prostate cancer tumor removal surgery. Our group is developing a miniaturized Coherent Anti-Stokes Raman scattering (CARS) system to identify malignant prostate tissue and tumor margin without optical labels or contrast agents. We have successfully finished the design of a high precision, label-free microendoscope based on the integration of CARS, microelectromechanical systems (MEMS), and four-wave mixing (FWM) noise suppression technologies. The 14 mm transversal diameter of the round-shaped CARS microendoscope probe paves the way towards future handheld multimodal CARS imaging for real time minimally invasive prostate cancer diagnosis. We have examined the feasibility of multimodal prostate imaging with CARS and second harmonic generation (SHG) using patient specimen and mouse models. The next step will be in vivo imaging and algorithm development with the all-fiber microendoscope system. This work presents a significant milestone in CARS endoscopy development using micro optics and MEMS mirror which greatly reduce the size of CARS endoscopy while keeping high imaging definition quality.

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号