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首页> 美国政府科技报告 >Interaction Between Noise and Lesion Modeling Errors on EEG Source Localization Accuracy.
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Interaction Between Noise and Lesion Modeling Errors on EEG Source Localization Accuracy.

机译：噪声与病变模型误差在脑电信号源定位精度上的相互作用。

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EEG dipole source reconstruction requires the assumption of a source model and of a conductive head model. Head-modeling errors and measurement noise in the EEG induce localization errors in the results of EEG source analysis. In this study effects of brain lesions on EEG dipole source localization have been investigated by computer simulation. We present a sensitivity study quantifying the effect on source localization accuracy of the interaction between the uncertainty in lesion conductivity assignment (LCA) and various levels of signal to noise ratio (SNR) in the EEGs. An inverse dipole fitting procedure, based on simulated noiseless EEG measurements and with SNR 5, 10 and 15, was carried out in 5 pathological situations, assuming an incorrect LCA ranging from a half to twice the real value. Incorrect LCA in noiseless conditions led to markedly wrong source reconstruction for high lesion conductivity values (localization errors up to 1.7 cm). We propose a method based on residual error analysis to improve lesion conductivity estimate. This procedure can identify lesion tissue conductivity with only a few percent error reducing the LE to value given by noise only.

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