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Comparison of Efficacy and Frequency of Screening and Selected Treatment Modalities for Prostate Cancer in African American and White Men

机译:非裔美国人和白人男性前列腺癌筛查和选择治疗方式的疗效和频率比较

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Prostate cancer mortality among African-American is twice than for whites. The aim of the present research concept development proposal was to determine the feasibility of conducting a study to evaluate differences in prostate cancer screening and treatment practices between African-American and White men. A case-control study where New Jersey residents dying of prostate cancer between the ages of 55 and 79 years during the period July 1, 1997 through June 30, 2000 are being enrolled as cases. Controls are a representative group of New Jersey male residents ascertained from HCFA files, matched to the cases on age and race. Till December 15, 1999, 198 cases and 126 controls have been recruited into the study. The majority of patients were Whites (85.9% of cases and 86.5% of controls) and the response rate was 70%. The frequency of PSA screening among cases was 15.9% as compared to 38.9% among controls. Only 12 patients with localized prostate cancer were recruited into the study and four (33.3%) of them had prostatectomy. Because of small numbers, we were unable to assess screening and treatment differences by race. In conclusion, although the number of patients recruited were too small for valid conclusion, we have demonstrated the feasibility of conducting a case-control study to evaluate racial differences in the frequency of screening and early treatment for prostate cancer. Based on the pilot data, a grant proposal for a major study is under preparation.

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