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首页> 美国政府科技报告 >Real-Time Monitoring and Control Methodologies to Aid in the Study of ProteinInteractions for Biosensor Applications
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Real-Time Monitoring and Control Methodologies to Aid in the Study of ProteinInteractions for Biosensor Applications

机译：实时监测和控制方法，以帮助生物传感器应用的蛋白质相互作用研究

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There is an emergent need for portable, inexpensive, reusable, and reliablesensors of environmental contaminants for both military and civilian uses. The development and study of such sensors is crucial for many applications. Among others, we mention measuring groundwater and waste water contamination, monitoring processes for agricultural and food products, and detecting soil contamination. In addition, such a technology is key to many medical procedures. The use of these sensors may be required on a continual and/or on a regular basis. In that respect, optically based sensors of protein interactions-such as those utilizing the optical phenomenon of Surface Plasmon Resonance (SPR)-show promise in producing sensory systems that are reusable, precise and portable for a range of applications. This proposal is to develop a computing platform to be used in the real-time monitoring, studying, and control of protein interactions. In particular, this platform allows the adaptive control of biosensor devices by integrating various data analysis and decision support modules, which could be used in a real-time fashion to control on-going experiments or synthesize and schedule new experiments in a distributed environment.

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