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Analyses of inter- and intra-patient variation in the V3 loop of the HIV-1 envelope protein.

机译：分析HIV-1包膜蛋白的V3环中的患者间和患者内的变异。

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The third hypervariable domain of the HIV-1 gp120 envelope protein (V3) has been the focus of intensive sequencing efforts. To date, nearly one thousand V3 loop sequences have been stored in the HIV sequence database. Studies have revealed that the V3 loo ...

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作者
B. Korber G. Myers S. Wolinsky;
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年度 1991
页码 1-19
总页数 19
原文格式 PDF
正文语种 eng
中图分类工业技术;
关键词
AIDS Virus; Amino Acid Sequence; Antigens; Biological Variability; Data Analysis; Data Base Management; EDB/550200; EDB/550400; EDB/550700; HIV-1; Meetings; Membrane Proteins; Protein Structure; Vaccines;

机译：艾滋病病毒;氨基酸序列;抗原;生物学变异;数据分析;数据库管理; EDB / 550200; EDB / 550400; EDB / 550700; HIV-1;会议;膜蛋白;蛋白质结构;疫苗;

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专利

1. The effect of low-profile serine substitutions in the V3 loop of HIV-1 gp120 IIIB/LAI on the immunogenicity of the envelope protein. [J] . Peet NM, McKeating JA, de-Souza JB, Virology . 1998,第1期

机译：HIV-1 gp120 IIIB / LAI V3环中低调丝氨酸取代对包膜蛋白免疫原性的影响。
2. Short Communication: Man1-2Man-Binding Anti-HIV Lectins Enhance the Exposure of V2i and V3 Crown Neutralization Epitopes on the V1/V2 and V3 Hypervariable Loops of HIV-1 Envelope [J] . Jan Muzafar, Upadhyay Chitra, Sharma Aman, AIDS Research and Human Retroviruses . 2017,第9期

机译：短期通信：MAN1-2MAN结合抗HIV凝集素增强了v1 / v2和V3高变循环的V2i和V3冠中和缺陷的暴露
3. Intraprotomer masking of third variable loop (V3) epitopes by the first and second variable loops (V1V2) within the native HIV-1 envelope glycoprotein trimer [J] . Li Liu, Raffaello Cimbro, Paolo Lusso, Proceedings of the National Academy of Sciences of the United States of America . 2011,第50期

机译：天然HIV-1包膜糖蛋白三聚体中的第一个和第二个可变环（V1V2）对第三个可变环（V3）表位的内旋分子掩盖
4. Modeling Inter- and Intra-Patient Anatomical Variation Using a Bilinear Model [C] . Yongwon Jeong, Radke, R.J. . 2006

机译：使用双线性模型对患者之间和患者内部的解剖变异进行建模
5. Studies of Protein Interactions and Knowledge-Based Drug Design: (A) The Electrostatic Nature of Recognition Between HIV-1 gp120 V3 Loop and Coreceptors CCR5/CXCR4, (B) Complement System Inhibition by Compstatin Family Peptides [D] . Lopez de Victoria Suarez, Aliana 2012

机译：蛋白质相互作用和基于知识的药物设计的研究：（A）HIV-1 gp120 V3环与共受体CCR5 / CXCR4之间识别的静电性质，（B）坎普他汀家族肽对补体系统的抑制作用
6. Short Communication: Manα1-2Man-Binding Anti-HIV Lectins Enhance the Exposure of V2i and V3 Crown Neutralization Epitopes on the V1/V2 and V3 Hypervariable Loops of HIV-1 Envelope [O] . Muzafar Jan, Chitra Upadhyay, Aman Sharma, -1

机译：简短交流：结合Manα1-2Man的抗HIV凝集素可增强HIV-1信封的V1 / V2和V3高变环上的V2i和V3冠中和表位的暴露
7. Intraprotomer masking of third variable loop (V3) epitopes by the first and second variable loops (V1V2) within the native HIV-1 envelope glycoprotein trimer [O] . Liu, Li, Cimbro, Raffaello, Lusso, Paolo, 2011

机译：天然HIV-1包膜糖蛋白三聚体中的第一个和第二个可变环（V1V2）对第三个可变环（V3）表位的内旋分子掩盖

Analyses of inter- and intra-patient variation in the V3 loop of the HIV-1 envelope protein.

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