首页> 美国政府科技报告 >Genetic Recombination in Mammalian Cells in Culture. Progress Report, August 1, 1981-July 31, 1982

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Genetic Recombination in Mammalian Cells in Culture. Progress Report, August 1, 1981-July 31, 1982

机译：哺乳动物细胞培养中的遗传重组。进展报告，1981年8月1日至1982年7月31日

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A glycine requiring hybrid, synthesized from two independent glycine requiring non-complementary mutants, was examined for its ability to produce glycine independent progeny spontaneously. The hybrid produced glycine independent progeny at a rate two orders of magnitude above the spontaneous mutation rate of either parent culture. Karyotype analysis of the progeny indicated a high incidence of rearrangement in one chromosome accompanying the change to glycine independence. These observations are compatible with a recombination process. (ERA citation 08:006188)

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作者
Morse, M. L.;
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年度 1982
页码 1-23
总页数 23
原文格式 PDF
正文语种 eng
中图分类工业技术;
关键词
Mutants; Cell cultures; Animal cells; Hamsters; Gene recombination; Mutation frequency; Biosynthesis; Glycine; Chromosomal aberrations;

机译：突变体;细胞培养;动物细胞;仓鼠;基因重组;突变频率;生物合成;甘氨酸;染色体畸变;

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机译：会议报告：31届国际哺乳动物基因组会议，哺乳动物遗传学和基因组学：从分子机制到翻译应用
2. Efficient reversal of phiC31 integrase recombination in mammalian cells [J] . Alfonso P. Farruggio, Christopher L. Chavez, Carlos L Mikell Biotechnology Journal: Healthcare,Nutrition,Technology . 2012,第11期

机译：哺乳动物细胞中phiC31整合酶重组的有效逆转
3. Critical amino acid residues within the varphiC31 integrase DNA-binding domain affect recombination activities in mammalian cells. [J] . Liesner R, Zhang W, Noske N, Human gene therapy . 2010,第9期

机译：varphiC31整合酶DNA结合域中的关键氨基酸残基影响哺乳动物细胞中的重组活性。
4. DESIGN OF FLEXIBLE ASSEMBLY SYSTEMS: Progress Report to August 24, 1999 [C] . Wilbert E. Wilhelm, Radu Gadidov, Narameth Nananukul, NSF Design Manufacturing Research Conference . 2000

机译：灵活装配系统设计：进度向1999年8月24日的进度报告
5. Studies on sister chromatid recombination in mammalian cells [D] . Hartlerode, Andrea Jean 2010

机译：哺乳动物细胞中姐妹染色单体重组的研究
6. Meeting Report: 31st International Mammalian Genome Conference Mammalian Genetics and Genomics: From Molecular Mechanisms to Translational Applications [O] . Gabriela Sánchez-Andrade, Jacob Moskowitz, Selene Howe, -1

机译：会议报告：第31届国际哺乳动物基因组会议哺乳动物遗传学和基因组学：从分子机制到翻译应用
7. New catalysts for the indirect liquefaction of coal. Second annual technical report, August 1, 1981-July 31, 1982 [O] . G.A. Melson 1982

机译：煤间接液化的新催化剂。第二届年度技术报告，1981年8月1日 - 1982年7月31日

Genetic Recombination in Mammalian Cells in Culture. Progress Report, August 1, 1981-July 31, 1982

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