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Effect of Sodium Fluoride on Skeletal Mass in Primary Osteoporosis

机译:氟化钠对原发性骨质疏松症患者骨量的影响

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The administration of NaF plus Ca to a group of eleven patients with primary osteoporosis did not result in an increase in TBCa as measured by TBNAA or in BMC by photon absorptiometry. However, the group of osteoporotic patients receiving Ca alone differed significantly from the group receiving NaF, with initial increase in TBCa, although the treatment of Ca was maintained for only one year. A possible explanation for the lack of effect of NaF here and the previously reported beneficial effect may be the absence of concomitant administration of vitamin D. However, no clinical or consistent laboratory manifestation of osteomalacia were observed in the patients. (ERA citation 03:001449)

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