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Chemical Changes in Erythromycin and Related Antibiotics During Radiation Sterilization

机译：辐射灭菌过程中红霉素及相关抗生素的化学变化

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The effect of electron radiation of an energy of 10 MeV on chemoradiation changes occuring in erythromycin base and its esters have been studied. No radiation damages of the molecule which could effect its antibiotic power have been found. The gaseous products formed are mainly due to the decomposition of the 14-member erythronolide and the ester chain. No change in the desosamine system particularly in the N,N-dimethylamine arrangement have been observed. (Atomindex citation 08:314993)

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Achmatowicz-Szmajke, T.; Bryl-Sandelewska, T.; Blum, A.; Witkowska, K.;
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年度 1973
页码 1-13
总页数 13
原文格式 PDF
正文语种 eng
中图分类工业技术;
关键词
Antibiotics ; Erythromycin ; Radiolysis ; Chemical radiation effects ; Dodecanoic acid ; Esters ; Gases ; Irradiation ; Mev range 01-10 ; Octadecanoic acid ; Prompt electrons ; Propionic acid ; Radiation doses ; Radiosterilization ; Sterilization ; Sulfates;

机译：抗生素;红霉素;辐解;化学辐射效应;十二烷酸;酯类;气体;辐照; mev范围01-10;十八烷酸;瞬发电子;丙酸;辐射剂量;放射性杀菌;灭菌;硫酸盐;

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1. Degradation of antibiotics and antibiotic resistance genes in erythromycin fermentation residues using radiation coupled with peroxymonosulfate oxidation [J] . Chu Libing, Chen Dan, Wang Jianlong, Waste Management . 2019,第AUGa期

机译：辐射结合过硫酸氢盐氧化降解红霉素发酵残基中的抗生素和抗生素抗性基因
2. Degradation of macrolide antibiotic erythromycin and reduction of antimicrobial activity using persulfate activated by gamma radiation in different water matrices [J] . Chu Libing, Zhuan Run, Chen Dan, Chemical engineering journal . 2019,第期

机译：不同水基质中γ辐射激活的过硫酸盐在不同水基质中脱硫的降解大环内酯抗生素红霉素和减少抗微生物活性
3. Sterility and Radiostability of Amoxicillin and Cefaclor Antibiotics Sterilized by Gamma Irradiation [J] . British Journal of Pharmaceutical Research . 2014,第17期

机译：γ射线灭菌的阿莫西林和头孢克洛抗生素的不育性和放射稳定性
4. Radiochemical Sterilization of Absorbable Suture Using 5 kGy Gamma Radiation [C] . J.R. Quirk, B.L. Anneaux, J. T. Corbett, Annual meeting of the Society For Biomaterials . 2002

机译：5 kGy伽玛射线可吸收缝线的放射化学灭菌
5. Biosynthesis of the macrolide antibiotics methymycin and erythromycin. [D] . Lambalot, Ralph Harold. 1994

机译：大环内酯类抗生素甲基霉素和红霉素的生物合成。
6. Radiation Sterilization of Anthracycline Antibiotics in Solid State [O] . A. Kaczmarek, J. Cielecka-Piontek, P. Garbacki, 2013

机译：固态蒽环类抗生素的辐射灭菌
7. Physicochemical Properties and Stability in the Acidic Solution of a New Macrolide Antibiotic, Clarithromycin, in Comparison with Erythromycin. [O] . Yasuo NAKAGAWA, Shigeru ITAI, Tsuguchika YOSHIDA, 1992

机译：与红细胞霉素相比，新型大环内酯抗生素酸性溶液酸性溶液中的物理化学性质及稳定性。
8. Effect of Aliphatic Alcohols as Radiation Protection on the Radiation Sterilization of Antibiotics by gamma Rays of Cobalt 60 [R] . Arumbinang, H., Zainul, K., Soediromargoso, S., 1978

机译：脂肪醇作为辐射防护剂对γ射线γ射线对抗生素辐射灭菌的影响

Chemical Changes in Erythromycin and Related Antibiotics During Radiation Sterilization

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