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TESTING FOR THE MUTAGENICITY OF IRRADIATED STRAWBERRIES FED TO RATS IN A HOST-MEDIATED ASSAY WITH NEUROSPORA AS INDICATOR ORGANISM

机译：利用神经生物作为指示器生物对宿主介导的大鼠放射性草莓的致突变性进行检测

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In this system an indicator organism is injected into the peritoneal cavity of a rodent, and then the animal is treated with the chemical to be checked for mutagenic activity. The indicator organism is then removed from the test animal and tested for mutations induced during its period of incubation in the mammalian host. Gabridge and Legator have used the induction of reverse mutations of histidine-requiring mutants of Salmonella typhimurium as an indicator system. Because this assay will pick up only certain classes of genetic alterations, it does not yield precise data on the frequency of induction of all types of mutations. In evaluating any mutagen for its relative hazard to man, it is important to know whether it is weak, moderate, or potent with regard to the induction of forward gene mutations.

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作者
H. V. Malling; F. J. de Serres; T. Mitcnell;
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年度 1971
页码 1-28
总页数 28
原文格式 PDF
正文语种 eng
中图分类工业技术;
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1. Utilizing the Pig-a Assay to Assess In Vivo Mutagenicity in An Integrated Testing Strategy and Comparing Pig-a to the TGR Mutation Assay [J] . Ji Z., Sosinski L. K., Visconti N., Environmental and molecular mutagenesis. . 2015,第Suppla1期

机译：在综合测试策略中使用Pig-a分析评估体内致突变性，并将Pig-a与TGR突变分析进行比较
2. Evaluation of the repeated-dose liver and gastrointestinal tract micronucleus assays with 22 chemicals using young adult rats: Summary of the collaborative study by the Collaborative Study Group for the Micronucleus Test (CSGMT)/The Japanese Environmental Mutagen Society (JEMS) - Mammalian Mutagenicity Study Group (MMS) [J] . Hamada Shuichi, Ohyama Wakako, Takashima Rie, Mutation Research - Genetic Toxicology and Environmental Mutagenesis . 2015,第Null期

机译：使用成年大鼠评估22种化学物质的重复剂量肝和胃肠道微核分析的结果：微核试验合作研究小组（CSGMT）/日本环境诱变学会（JEMS）的合作研究总结-哺乳动物诱变研究群组（MMS）
3. The use of a novel Vibrio harveyi luminescence mutagenicity assay in testing marine water for the presence of mutagenic pollution [J] . Beata Podgorska, Ksenia Pazdro, Janusz Pempkowiak, Marine pollution bulletin . 2007,第6期

机译：新型哈氏弧菌发光诱变测定法在海水中检测是否存在诱变污染
4. ECOTOXICOLOGICAL ASSAYS OF DIETHYLTOLUAMIDE AND LEMONGRASS ESSENCIAL OIL IN IRRADIATED AND NON-IRRADIATED AQUATIC ORGANISMS [C] . Giovana T. Gimiliani, Sizue O. Rogero, Gisela A. Martini, International Nuclear Atlantic Conference . 2018

机译：辐照和非照射水生生物中二乙基磺酰胺和柠檬草精油的生态毒理学测定
5. Using learning principles in predictive risk assessment: A pesticide toxicology assay for insects using the honey bee (Apis mellifera) as an indicator organism. [D] . Buckbee, Dolores Ann. 1997

机译：在预测性风险评估中使用学习原理：使用蜜蜂（蜜蜂）作为指示生物的杀虫剂毒理学测定法。
6. The evaluation of chemical mutagenicity data in relation to population risk: some factors affecting the host-mediated assay response. [O] . E Zeiger 1973

机译：与人群风险相关的化学诱变数据评估：一些影响宿主介导的测定反应的因素。
7. The evaluation of chemical mutagenicity data in relation to population risk: some factors affecting the host-mediated assay response. [O] . Zeiger, E 1973

机译：与人群风险相关的化学诱变数据评估：一些影响宿主介导的测定反应的因素。

TESTING FOR THE MUTAGENICITY OF IRRADIATED STRAWBERRIES FED TO RATS IN A HOST-MEDIATED ASSAY WITH NEUROSPORA AS INDICATOR ORGANISM

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