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Heritable Genetic Changes in Cells Recovered from Irradiated 3D Tissue Constructs.

机译：从辐照的3D组织构建体中恢复的细胞遗传性遗传变化。

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Combining contemporary cytogenetic methods with DNA CGH microarray technology and chromosome flow-sorting increases substantially the ability to resolve exchange breakpoints associated with interstitial deletions and translocations, allowing the consequences of radiation damage to be directly measured at low doses, while also providing valuable insights into molecular mechanisms of misrepair processes that, in turn, identify appropriate biophysical models of risk at low doses. The following aims apply to cells recovered from 3D tissue constructs of human skin and, for the purpose of comparison, the same cells irradiated in traditional 2D cultures. The project includes research complementary to NASA/HRP space radiation project.

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作者
Cornforth, M.;
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年度 2012
页码 1-9
总页数 9
原文格式 PDF
正文语种 eng
中图分类工业技术;
关键词
Genetics; Chromosomes; DNA; Interstitials; Microarray technology; Radiations; Damage; Irradiation;

机译：遗传学;染色体; DNa;间隙;微阵列技术;辐射;损伤;辐射;

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2. Tissue engineering of flexor tendons: the effect of a tissue bioreactor on adipoderived stem cell-seeded and fibroblast-seeded tendon constructs. [J] . Angelidis IK, Thorfinn J, Connolly ID, Journal of Hand Surgery. American Volume . 2010,第9期

机译：屈肌腱的组织工程：组织生物反应器对脂肪来源的干细胞接种和成纤维细胞接种的腱构造的影响。
3. Reciprocal interactions between cells and extracellular matrix during remodeling of tissue constructs. [J] . Wakatsuki T, Elson EL Biophysical Chemistry: An International Journal Devoted to the Physical Chemistry of Biological Phenomena . 2003,第1a3期

机译：在组织构造的重塑过程中，细胞与细胞外基质之间的相互作用。
4. Genetic variability and heritability on Kipas Putih soybean mutant lines using gamma rays irradiation (M3 generation) [C] . Nilahayati, Rosmayati, D S Hanafiah, International Conference on Agriculture, Environment, and Food Security . 2017

机译：使用γ射线照射丙脂菌腐豆突变线遗传变异性和遗传性（M3代）
5. In vitro prevascularization of 3D tissue constructs. [D] . Marshall, Lauren E. 2013

机译：3D组织构建体的体外预血管化。
6. Genetic Analysis of T Cell Lymphomas in Carbon Ion-Irradiated Mice Reveals Frequent Interstitial Chromosome Deletions: Implications for Second Cancer Induction in Normal Tissues during Carbon Ion Radiotherapy [O] . Benjamin J. Blyth, Shizuko Kakinuma, Masaaki Sunaoshi, -1

机译：碳离子辐照小鼠中T细胞淋巴瘤的遗传分析显示出频繁的间质染色体缺失：碳离子放射治疗期间正常组织中第二次癌症诱导的意义。
7. Heritable Genetic Changes in Cells Recovered From Irradiated 3D Tissue Contracts. Final report [O] . Cornforth, Michael N. 2013

机译：从辐照的3D组织合约中恢复的细胞遗传性遗传变化。总结报告

Heritable Genetic Changes in Cells Recovered from Irradiated 3D Tissue Constructs.

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