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Classification of superficial lesions of the eye with an optical biopsy system: First trials with the Los Alamos instrument.

机译:使用光学活检系统对眼表浅部病变进行分类:首次使用Los alamos仪器进行试验。

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The clinical diagnosis of a lesion often requires that a histological analysis be made of a physical specimen of the suspect tissue. In the present work, the authors have utilized an optical biopsy system (OBS) developed at Los Alamos National Laboratory which is safe for patient use and provides a large amount of optical data from the sampled tissue. An earlier version of this system has been used to study age-related changes in the ocular lens (10). The purpose of the present study is to establish the potential clinical utility of the OBS by determining if characteristic features in the optical signatures, obtained from a variety of ophthalmic lesions, are correlated with the histological features of tissue biopsies obtained from these patients.

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