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Final Report on the Peri-/Postnatal Evaluation of Hexachloro-1,3-Butadiene (HCBD)Toxicity in CD Rats

机译：关于CD大鼠六氯-1,3-丁二烯（六氯丁二烯）毒性的围产期/产后评价的最终报告

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Hexachloro-1,3-butadiene (HCBD) is an agricultural and industrial chemical and by-product which has been identified as a neprhotoxin in both humans and laboratory animals. It is used industrially to recover chlorine-containing gas, as a fluid for gyroscopes and in the production of lubricants and rubber. HCBD is also a by-product of chlorinated hydrocarbon production. Agriculturally, it is used as a fumigant on grapes. HCBD contamination has been detected in air, water and soil surrounding chemical manufacturing plants and toxic waste landfills and in food and beverages. The current study was undertaken to examine peri-/postnatal development of the rat during maternal exposure to HCBD in the diet during late gestation and lactation with particular attention to structural and functional renal endpoints.

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Field, E. A.; Sleet, R. B.; Price, C. J.; Marr, M. C.; Myers, C. B.;
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年度 1990
页码 1-120
总页数 120
原文格式 PDF
正文语种 eng
中图分类工业技术;
关键词
Toxicity; Chemical analysis; Embryo development; Ovum implantation; Organ weight; Tables(Data);

机译：毒性;化学分析;胚胎发育;卵子植入;器官重量;表（数据）;

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专利

1. A Review on Hexachloro-1,3-butadiene (HCBD): Sources, Occurrence, Toxicity and Transformation [J] . Kong Qingqing, Wang Yu, Yang Xin Bulletin of Environmental Contamination and Toxicology . 2020,第1期

机译：六氯-1,3-丁二烯（HCBD）的综述：来源，发生，毒性和转型
2. Nephrotoxicity of hexachloro-1:3-butadiene in the male Hanover Wistar rat; correlation of minimal histopathological changes with biomarkers of renal injury [J] . SwainA., TurtonJ., ScudamoreC., Journal of applied toxicology . 2012,第5a6期

机译：六氯-1：3-丁二烯对雄性汉诺威Wistar大鼠的肾毒性;最小组织病理学改变与肾损伤生物标志物的相关性
3. Hyaline droplet accumulation in kidney of rats treated with hexachloro-1:3-butadiene: Influence of age, dose and time-course [J] . CristoforiP., DefazioR., ChiusoloA., Journal of applied toxicology . 2013,第3a4期

机译：六氯-1：3-丁二烯处理的大鼠肾脏中的透明液滴聚集：年龄，剂量和时程的影响
4. Pre/peri- or postnatal medical history on the risk of brain tumors in children and adolescents: reports from CEFALO multicenter case-control study [C] . Xiaochen Shu, Maria Feychting, Martin Roeoesli, Annual conference of the International Society of Exposure Science . 2014

机译：儿童和青少年脑肿瘤风险的产前/产前或产后病史：CEFALO多中心病例对照研究的报告
5. Singled-walled carbon nanotubes produced by induction thermal plasma: Cytotoxicity evaluation of the feedstock materials and the final product for a potential bone application. [D] . Alinejad, Yasaman. 2013

机译：通过感应热等离子体生产的单壁碳纳米管：对原料和最终产品的细胞毒性评估，以评估潜在的骨骼应用。
6. Erratum to: Criteria for Reporting and Evaluating ecotoxicity Data (CRED): comparison and perception of the Klimisch and CRED methods for evaluating reliability and relevance of ecotoxicity studies [O] . Robert Kase, Muris Korkaric, Inge Werner, -1

机译：勘误至：报告和评估生态毒性数据的标准（CRED）：对Klimisch和CRED方法评估生态毒性研究的可靠性和相关性的方法的比较和认识
7. Evaluation of the Pre-, Peri-, and Postnatal Toxicity of Monoethanolamine in Rats Following Repeated Oral Administration during Organogenesis [O] . J. Hellwig, A. B. Liberacki 1997

机译：在有机组织期间重复口服给药后大鼠单乙醇胺的预先评价单乙醇胺的预期，Peri和产后毒性
8. Developmental Toxicity Screen for Diethanolamine (CAS No. 111-42-2) Administered211 by Gavage to Sprague-Dawley (CD (Trade Name)) Rats on Gestational Days 6 through 211 19: Evaluation of Dams and Pups through Postnatal Day 21. Final Study Report [R] . Price, C. J. 1999

机译：二乙醇胺（Cas No. 111-42-2）的发育毒性筛选通过管饲给予sprague-Dawley（CD（商品名））大鼠在妊娠第6至第211天施用大鼠19：通过产后第21天评估水坝和幼仔。最终研究报告

Final Report on the Peri-/Postnatal Evaluation of Hexachloro-1,3-Butadiene (HCBD)Toxicity in CD Rats

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