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Mycoplasma genitalium Protein Resembling the 'Mycoplasma pneumoniae' Attachment Protein

机译:生殖道支原体蛋白质类似于'肺炎支原体'附着蛋白

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In previous studies with hyperimmune rabbit sera and monoclonal antibodies against P1 protein of M. pneumoniae, evidence was obtained of a shared antigenic determinant with a single protein of M. genitalium. Because of biological and morphological similarities between these two human Mycoplasma species, attempts were made to characterize this cross-reacting protein of M. genitalium (designated MgPa). The protein was surface exposed, and had an estimated molecular weight of 140 K daltons. Electron microscopy using monoclonal antibodies produced against either MgPa or P1 demonstrated that MgPa is located over the surface of the terminal structure of M. genitalium which is covered by a nap layer. These immunologic and morphologic findings suggest that the MgPa protein of M. genitalium could be the counterpart of the P1 protein of M. pneumoniae. (Copyright (c) 1987, American Society for Microbiology.)

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