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New Vaccine Development Establishing Priorities. Volume 1. Diseases of Importance in the United States

机译：新疫苗开发确立优先事项。第1卷。美国的重要疾病

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The Institute of Medicine (IOM) convened a group of experts to develop model for setting priorities among vaccines for diseases of importance to the general U.S. population. IOM obtained and used relevant data so as to quantify the various components of the decision making aspects of the model e.g., epidemiological data, mortality and morbidity data, cost of illness, scientific readiness, incidence and prevalence of target diseases, cost effectiveness, patient and physician acceptance, safety and efficacy, etc. Using the model, IOM evaluated five vaccines--that IOM and the NIAID Steering Group had agreed were ready scientifically for accelerated development--and provided NIAID with a list of these candidate vaccines in order of priority. In a second phase of the study, IOM will consider candidate vaccines for diseases of importance to less technologically advanced nations, and develop a model for setting priorities among vaccines whose development could be accelerated.

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