首页> 美国政府科技报告 >Toxicology and Carcinogenesis Studies of HC Blue No. 2 (((((Hydroxyethyl)Amino) - Nitrophenyl)IminoBis(Ethanol)) (CAS No. 33229-34-4) in F344/N Rats and B6C3F1 Mice (Feed Studies)
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Toxicology and Carcinogenesis Studies of HC Blue No. 2 (((((Hydroxyethyl)Amino) - Nitrophenyl)IminoBis(Ethanol)) (CAS No. 33229-34-4) in F344/N Rats and B6C3F1 Mice (Feed Studies)

机译:HC蓝2号(((((羟乙基)氨基) - 硝基苯基)氨基双(乙醇))(Cas号33229-34-4)在F344 / N大鼠和B6C3F1小鼠中的毒理学和癌变研究(饲料研究)

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HC Blue No. 2 is a nitrophenylenediamine derivative used as a semipermanent hair dye. Semipermanent hair color products are generally 'shampoo-in' preparations that are applied to the hair, lathered, and then allowed to remain in contact with the hair and scalp for 30-45 minutes. The present report summarizes the results of 2-year toxicology and carcinogenesis studies of HC Blue No. 2 given in the diet of F344/N rats and B6C3F(sub 1) mice. The oral (feed) route of administration was selected to maximize chances of detecting systemic effects associated with chemical administration.

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