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Detection of Hydroxy-Nitro-PAHs (-Polycyclic Aromatic Hydrocarbons) in an Ambient Air Particulate Extract Using Bioassay Directed Fractionation

机译：利用生物测定定向分离法检测环境空气颗粒提取物中的羟基 - 多环芳烃（多环芳烃）

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摘要

Urban air particles contain extractable organic matter which has both mutagenic and carcinogenic activity. Detection of the specific compounds responsible for mutagenic activity has been limited by the complexity of these extracts and the presence of highly polar components which have been difficult to identify. To facilitate identifications, these extracts must be separated into substantially less complex fractions and analyzed with newer analytical techniques. Bioassay-directed fractionation has been proposed as the most cost and time effective approach to identifying mutagenic compounds in complex mixtures by directing the analytical and identification research effort toward only significantly mutagenic fractions. This approach should be especially useful for the detection of heretofore unknown constituents of the matrix as the methods are not directed to or developed for specific compounds or compound classes.

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Nishioka, M. G. ; Howard, C. C. ; Lewtas, J.;
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年度 1985
页码 1-18
总页数 18
原文格式 PDF
正文语种 eng
中图分类工业技术;
关键词
Aromatic polycyclic hydrocarbons; Bioassay; Distillation; Particles; Air pollution; Mutagens; Carcinogens; Chemical analysis; Industrial wastes; Residential buildings; Extraction; Mass spectroscopy;

机译：芳香族多环烃;生物测定;蒸馏;颗粒;空气污染;致突变物;致癌物;化学分析;工业废物;住宅建筑;提取;质谱;

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专利

1. An Improved Fractionation Procedure for the Bioassay-Directed Chemical Analysis of Ambient Air Particulate Extracts [J] . Mikio ZINBO, Dennis SCHUETZLE, Dennis P. H. HSIEH, Analytical Sciences . 1992,第4期

机译：改进的分馏程序，用于环境空气微粒提取物的生物测定指导化学分析
2. Kinetics of ROS generation induced by polycyclic aromatic hydrocarbons and organic extracts from ambient air particulate matter in model human lung cell lines [J] . Libalova Helena, Milcova Alena, Cervena Tereza, Mutation Research - Genetic Toxicology and Environmental Mutagenesis . 2018,第期

机译：多环芳烃和来自模型人肺细胞系中的多环芳烃和有机萃取物诱导的ROS生成的动力学
3. Airborne particulates and polycyclic aromatic hydrocarbons (PAHs) in ambient air in Donghe, Northern China [J] . WEI WANG, SHU TAO, WENTAO WANG, Journal of Environmental Science and Health . 2009,第9期

机译：中国北方东河市周围空气中的空气传播颗粒物和多环芳烃（PAH）
4. ATMOSPHERIC PRESSURE THERMAL DISSOCIATION CHEMICAL IONIZATION MASS SPECTROMETRY: MASS SPECTROMETRIC ANALYSES OF POLYCYCLIC AROMATIC HYDROCARBONS AND AMINO-ACIDS BY DIRECT SAMPLING IN AMBIENT AIR [C] . . 2005

机译：大气压热解离化学电离质谱：直接采样环境空气中多环芳烃和氨基酸的质谱分析
5. Gas/solid and gas/particle partitioning of polychlorinated dibenzodioxins, polychlorinated dibenzofurans and polycyclic aromatic hydrocarbons to filter surfaces and ambient atmospheric particulate material. [D] . Mader, Brian T. 2000

机译：多氯二苯并二恶英，多氯二苯并呋喃和多环芳烃的气体/固体和气体/颗粒分配，以过滤表面和周围的大气颗粒物。
6. A simple methodological validation of the gas/particle fractionation of polycyclic aromatic hydrocarbons in ambient air [O] . Yong-Hyun Kim, Ki-Hyun Kim -1

机译：环境空气中多环芳烃气体/颗粒分馏的简单方法论验证
7. Automated clean-up, separation and detection of polycyclic aromatic hydrocarbons in particulate matter extracts using a 2D-LC/2D-GC system : a method translation from two FIDs to two MS detectors [O] . Lim, Hwanmi, Ahmed, Trifa M., Bergvall, Christoffer, 2017

机译：使用2D-LC / 2D-GC系统自动净化，分离和检测颗粒物提取物中的多环芳烃：从两个FID转换为两个MS检测器的方法
8. Detection of Hydroxylated Nitro Aromatic and Hydroxylated Nitro Polycyclic Aromatic Compounds in an Ambient Air Particulate Extract Using Bioassay-Directed Fractionation [R] . Nishioka, M. G. , Howard, C. C. , Contos, D. A. , 1988

机译：生物测定定向分离检测环境空气颗粒提取物中羟基化硝基芳香和羟基化硝基多环芳烃

Detection of Hydroxy-Nitro-PAHs (-Polycyclic Aromatic Hydrocarbons) in an Ambient Air Particulate Extract Using Bioassay Directed Fractionation

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