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PROPERTIES OF ERYTHROCYTES WHICH MAY INFLUENCE THE CONVERSION OF PROFIBRINOLYSIN TO FIBRINOLYSIN

机译：可能影响纤维蛋白溶酶转化为纤维蛋白溶酶的红细胞特性

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Evidence is presented that erythrocytes adsorb urokinase, a urinary activator of plasma profibrinolysin, and that in the adsorbed state urokinase not only remains active but is "protected" from factors normally present in plasma. When washed red cells, devoid of components of the fibrinolytic system, are exposed to plasma they acquire simultaneously inhibitors to urokinase and an agent capable of lysing a fibrin clot. Evidence is presented that these acquired properties are the result of adsorption to the erythrocyte of factors present in plasma and that this adsorption is affected by the fibrinolytic status of the animal from which the plasma and erythrocytes are obtained. The significance of the erythrocyte in the development of in vivo fibrinolytic activity is discussed.

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S. N. KOLMEN; M. MASON GUEST; D. R. CELANDER;
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年度 1959
页码 1-11
总页数 11
原文格式 PDF
正文语种 eng
中图分类工业技术;
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机译：可能影响纤维蛋白溶酶转化为纤维蛋白溶酶的红细胞特性。

PROPERTIES OF ERYTHROCYTES WHICH MAY INFLUENCE THE CONVERSION OF PROFIBRINOLYSIN TO FIBRINOLYSIN

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