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Clinical Importance of the Drug Interaction between Statins and CYP3A Inhibitors. Inclusive Dates: 07/01/08 - 06/30/10.

机译：他汀类药物与CYp3a抑制剂药物相互作用的临床意义。包容性日期：07/01/08 - 06/30/10。

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The purpose of the current investigation was to detect adverse clinical outcomes associated with statins and CYP3A4 inhibitors. Our specific aim was to measure the relative hazard of muscle toxicity, kidney dysfunction, and hepatic dysfunction associated with statin 3A4 substrates compared to statin non-3A4 substrates with and without CYP3A4 inhibitor concomitancy.

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作者
Strom, B. L.;
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年度 2010
页码 1-20
总页数 20
原文格式 PDF
正文语种 eng
中图分类工业技术;
关键词
Statins; Drugs; Clinical medicine; Detection; Dysfunction; Hazards; Interactions; Kidney diseases; Muscles; Substrates; Toxicity; CYP3A4 inhibitor;

机译：他汀类药物;临床医学;检测;功能障碍;危害;相互作用;肾脏疾病;肌肉;基质;毒性; CYp3a4抑制剂;

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Clinical Importance of the Drug Interaction between Statins and CYP3A Inhibitors. Inclusive Dates: 07/01/08 - 06/30/10.

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