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首页> 美国政府科技报告 >NTP Report on the Toxicology Studies of Allyl Bromide (CAS NO. 106-95-6) in Genetically Modified (FVB Tg.AC Hemizygous) Mice Carcinogenicity Studies of Allyl Bromide in Genetically Modified (B6.129-Trp53(sup tm1Brd)(N5) Haploinsufficient) Mice (Dermal and Gavage Studies)
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NTP Report on the Toxicology Studies of Allyl Bromide (CAS NO. 106-95-6) in Genetically Modified (FVB Tg.AC Hemizygous) Mice Carcinogenicity Studies of Allyl Bromide in Genetically Modified (B6.129-Trp53(sup tm1Brd)(N5) Haploinsufficient) Mice (Dermal and Gavage Studies)

机译：NTp关于烯丙基溴（Cas NO.106-95-6）在转基因（FVB Tg.aC Hemizygous）小鼠中的毒理学研究报告转基因中烯丙基溴的致癌性研究（B6.129-Trp53（sup tm1Brd）（N5） ）Haploinsufficient）小鼠（皮肤和灌胃研究）

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Allyl bromide is primarily used as a starting material/ chemical intermediate in organic synthesis and as an intermediate in the manufacture of polymers/resins, synthetic perfumes, pharmaceuticals, agricultural chemicals, and other allyl compounds. It has been described as an insecticidal fumigant used in crop protection. Male and female FVB/N and C57BL/6 mice received allyl bromide (greater than 99% pure) by gavage and dermal application, respectively, for 2 weeks, and FVB/N, C57BL/6, Tg.AC hemizygous, and p53 haploinsufficient mice received allyl bromide by gavage for 40 weeks. Genetic toxicology studies were conducted in Salmonella typhimurium and mouse peripheral blood erythrocytes.

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