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首页> 美国政府科技报告 >Incidence of Respiratory Symptoms and Chronic Disease in a Non-Smoking Population as a Function of Long-Term Cumulative Exposure to Ambient Air Pollutants (Adventist Health Study of Smog Follow-Up Study). Volume 1. Final Report
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Incidence of Respiratory Symptoms and Chronic Disease in a Non-Smoking Population as a Function of Long-Term Cumulative Exposure to Ambient Air Pollutants (Adventist Health Study of Smog Follow-Up Study). Volume 1. Final Report

机译：非吸烟人群中呼吸系统症状和慢性病的发病率与长期累积暴露于环境空气污染物的函数关系（烟雾随访研究的复临健康研究）。第1卷。最终报告

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Data on occurrence and severity of chronic bronchitis and asthma, on occurrence of cancer, heart disease, and mortality, and on numerous lifestyle and air pollution exposure covariates were collected from a cohort of 6340 non-smoking California Seventh-day Adventists in 1987. Monthly pollutant exposures were estimated from ambient concentrations of seven air pollutants--ozone, NO2, SO2, TSP, PM10 estimated from TSP, PM2.5 estimated from visibility, and SO4--experienced by subjects during 1966-87. Statistical analyses estimated relationships between these health endpoints and long-term average ambient concentrations, adjusting for covariates. TSP, the pollutant most strongly related to health endpoints, was significantly related to occurrence of and increases in severity of chronic bronchitis and asthma and to occurrence of cancers in females. PM10 was associated with occurrence of chronic bronchitis and severity of asthma, and PM2.5 was significantly but less strongly associated with several respiratory endpoints. Ozone and SO4 were sigificantly associated with occurrence and severity of asthma. There were no significant associations between any health endpoint, SO2, and NO2. Multipollutant analyses were performed to investigate whether any of the significant relationships between pollutants and health endpoints were due to surrogate relationships with other pollutants.

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