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首页> 美国政府科技报告 >Growth and Growth Hormone Therapy in Turner Syndrome (Groei en Groeihormoon Behandeling bij Patienten met het Syndroom van Turner)
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Growth and Growth Hormone Therapy in Turner Syndrome (Groei en Groeihormoon Behandeling bij Patienten met het Syndroom van Turner)

机译：特纳综合症的生长和生长激素治疗（Groei en Groeihormoon Behandeling bij patienten遇见het syndroom van Turner）

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Turner syndrome is one of the most common chromosomal disorders. Short stature is, in addition to gonadal dysgenesis and several dysmorphic features, one of the main characteristics of Turner syndrome. The growth pattern of Dutch patients with Turner syndrome has not been reported so far. During the past few years an attempt was made to improve the final height of these patients with anabolic steroids. The effect on final height, however, has remained uncertain. Since the availability of biosynthetic growth hormone in 1985 it was possible to treat patients with short stature not due to classical growth hormone deficiency with growth hormone. The purpose of the study is to investigate the growth pattern and body proportions of Dutch patients with Turner syndrome, to evaluate the effect of growth hormone treatment on height, body proportions and craniofacial morphology, and to assess the safety of growth hormone therapy with special attention to the immune function.

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