首页> 外文OA文献 >The impact of approaches in improving male partner involvement in the prevention of mother-to-child transmission of HIV on the uptake of maternal antiretroviral therapy among HIV-seropositive pregnant women in sub-Saharan Africa: a systematic review and meta-analysis.
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The impact of approaches in improving male partner involvement in the prevention of mother-to-child transmission of HIV on the uptake of maternal antiretroviral therapy among HIV-seropositive pregnant women in sub-Saharan Africa: a systematic review and meta-analysis.

机译:系统评价和荟萃分析显示,改善男性伴侣参与预防母婴传播艾滋病毒对撒哈拉以南非洲地区艾滋病毒血清反应阳性孕妇采用孕产妇抗逆转录病毒治疗方法的影响:系统评价和荟萃分析。

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摘要

Objectives: To identify the approaches that are used in improving on male partner involvement in the prevention of mother-to-child transmission (PMTCT) of HIV and their impact on the uptake maternal antiretroviral therapy (ART) in sub-Saharan Africa (SSA).ududSetting: This was a systematic review and meta-analysis of published studies carried out in SSA at all levels of healthcare (primary, secondary, tertiary and community).ududParticipants: The participants of the studies included were HIV-positive pregnant women and breastfeeding mothers with their male partners. Studies were included if they were conducted in SSA and mentioned an approach used in improving male partner involvement with data on the impact on the uptake of maternal ART uptake.ududOutcomes: In the protocol, maternal ART uptake, infant prophylaxis, safe infant feeding options, condom use and family planning were envisaged. However, only maternal ART has been reported here due to limitations on the word count.ududResults: From an initial 2316 non-duplicate articles, 17 articles were included in the systematic review and meta-analysis. In the combined model, the ORs for complex community interventions, enhanced psychosocial interventions, verbal encouragement and invitation letters were 4.22 (95% CI 2.27 to 7.77), 2.29 (95% CI 1.42 to 7.69), 2.39 (95% CI 1.26 to 4.53) and 1.21 (95% CI 0.89 to 1.63), respectively, whereas in the model using adjusted ORs, enhanced psychosocial interventions had a higher effect than any other intervention. The heterogeneity was moderate using adjusted ORs.ududConclusion: Enhanced psychosocial interventions and complex community interventions increase male partner involvement and the uptake of PMTCT services more than any other intervention. Invitation letters had no effect. More randomised trials and observational studies (that have adjusted for potential confounders) are needed in the future.ududPROSPERO registration number: 42016032673.
机译:目标:确定在撒哈拉以南非洲(SSA)中用于改善男性伴侣预防艾滋病毒母婴传播(PMTCT)及其对摄取母体抗逆转录病毒疗法(ART)的影响的方法 ud ud设置:这是对SSA中所有医疗保健级别(主要,次要,第三级和社区)进行的已发表研究的系统评价和荟萃分析。 ud ud参与者:纳入研究的参与者是HIV阳性孕妇和与男性伴侣一起哺乳的母亲。如果研究是在SSA中进行的,则将其纳入研究范围,并提及一种用于改善男性伴侣参与的方法,并提供有关对母体ART摄取影响的数据。 ud ud结果:在方案中,母体ART摄取,婴儿预防,安全婴儿设想了喂养方式,使用避孕套和计划生育。但是,由于字数限制,此处仅报道了母体ART。 ud ud结果:从最初的2316篇非重复文章中,有17篇文章被纳入系统评价和荟萃分析。在组合模型中,复杂社区干预,增强型社会心理干预,口头鼓励和邀请函的OR分别为4.22(95%CI 2.27至7.77),2.29(95%CI 1.42至7.69),2.39(95%CI 1.26至4.53) )和1.21(95%CI为0.89至1.63),而在使用调整后OR的模型中,加强的社会心理干预措施的效果要高于其他干预措施。结论:加强的社会心理干预和复杂的社区干预比其他干预措施更能促进男性伴侣的参与和对PMTCT服务的吸收。邀请函无效。将来需要更多随机试验和观察性研究(已针对潜在的混杂因素进行了调整)。 ud udPROSPERO注册号:42016032673。

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