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Free-Energy Landscapes of Ion-Channel Gating Are Malleable: Changes in the Number of Bound Ligands Are Accompanied by Changes in the Location of the Transition State in Acetylcholine-Receptor Channels

机译：离子通道门控的自由能景观是可展望的：结合配体的变化伴随着乙酰胆碱受体通道中的过渡状态的变化

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Claudio Grosman;
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年度 2003
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1. Free-energy landscapes of ion-channel gating are malleable: changes in the number of bound ligands are accompanied by changes in the location of the transition state in acetylcholine-receptor channels. [J] . Grosman C Biochemistry . 2003,第50期

机译：离子通道门控的自由能态是可塑的：结合的配体数量的变化伴随着乙酰胆碱受体通道中过渡态位置的变化。
2. Weakening of ion-channel interactions of Na+ and Li+ in acetylcholine-receptor channels of frog skeletal muscle with an increase in agonist concentration. [J] . Manthey AA Pfluegers Archiv: European Journal of Physiology . 1998,第6期

机译：随着激动剂浓度的增加，蛙骨骼肌乙酰胆碱受体通道中Na +和Li +的离子通道相互作用减弱。
3. Generation of a Focused Set of GSK Compounds Biased toward Ligand-Gated Ion-Channel Ligands [J] . Anna Maria Capelli, Aldo Feriani, Giovanna Tedesco, Journal of chemical information and modeling . 2006,第2期

机译：偏向配体门离子通道配体的一组重点GSK化合物的生成
4. Lucifer Yellow CH modifies voltage-gated channels and a ligand-gated channel in a light-dependent manner [C] . Keita Takeuchi, Kiyonori Yoshi Brain IT . 2006

机译：Lucifer Yellow Ch以轻依赖性的方式改变电压门控通道和配体门控通道
5. Development of Small Molecule Ligands for Voltage-gated Potassium Channels and Functional Characterization of Voltage-gated Phosphatases [D] . Bell, Sarah C. 2010

机译：电压门控钾通道的小分子配体的开发和电压门控磷酸酶的功能表征
6. Free-energy Landscapes of Ion-channel Gating Are Malleable: changes in the number of bound ligands are accompanied by changes in the location of the transition state in acetylcholine-receptor channels [O] . CLAUDIO GROSMAN -1

机译：离子通道门控的自由能态具有可塑性：结合配体数量的变化伴随着乙酰胆碱受体通道中过渡态位置的变化
7. Predicted structure of the extracellular region of ligand-gated ion-channel receptors shows SH2-like and SH3-like domains forming the ligand-binding site. [O] . Gready, J. E., Ranganathan, S., Schofield, P. R., 1997

机译：配体门控离子通道受体的胞外区的预测结构显示形成配体结合位点的类SH2和类SH3域。

Free-Energy Landscapes of Ion-Channel Gating Are Malleable: Changes in the Number of Bound Ligands Are Accompanied by Changes in the Location of the Transition State in Acetylcholine-Receptor Channels

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