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首页> 外文OA文献 >Dramatic response of iris and retinal neovascularisation following usage of intravitreal ranibizumab as pre-operative adjunct in vitrectomy for advanced proliferative diabetic retinopathy
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Dramatic response of iris and retinal neovascularisation following usage of intravitreal ranibizumab as pre-operative adjunct in vitrectomy for advanced proliferative diabetic retinopathy

机译：玻璃体腔内雷珠单抗作为晚期增生性糖尿病性视网膜病变玻璃体切除术的术前辅助物后虹膜和视网膜新血管形成的剧烈反应

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摘要

A 37-year-old Malay woman presented with progressive deterioration in vision and was diagnosed with advanced proliferative diabetic retinopathy with neovascular glaucoma. Intravitreal ranibizumab injection (an anti-vascular endothelial growth factor) was administered prior to vitrectomy. Slit lamp assessment 2 days post-injection revealed significant regression of both iris and retinal neovascularisation. This resulted in adequate reduction of intra-ocular pressure prior to surgery. In addition, the regression of retinal vessels reduced the risk of intra-operative haemorrhage, thus aiding the surgical excision of the fibrovascular membranes. Periodic post-operative assessment in the first 3 weeks showed minimal inflammation and no recurrence of vitreous haemorrhage. This case illustrates that intravitreal ranibizumab has a role as an adjunct therapy prior to diabetic vitrectomy to significantly reduce the risk of intra-ocular haemorrhage.
机译：一名37岁的马来妇女表现出视力进行性恶化，并被诊断出患有晚期增生性糖尿病视网膜病变并伴有新生血管性青光眼。玻璃体切除术前玻璃体内注射兰尼单抗注射液（一种抗血管内皮生长因子）。注射后2天的裂隙灯评估显示虹膜和视网膜新血管形成均显着消退。这导致在手术前充分降低眼内压。另外，视网膜血管的退化减少了术中出血的风险，从而有助于外科手术切除纤维血管膜。术后3周的定期术后评估显示炎症最小，玻璃体出血没有复发。该病例说明玻璃体内雷珠单抗在糖尿病玻璃体切除术前具有辅助治疗作用，可显着降低眼内出血的风险。

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    Malisa A; Mae-Lynn CB;

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  • 年度 2011
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  • 正文语种 {"code":"en","name":"English","id":9}
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