首页> 外文OA文献 >The HIV-1 reverse transcriptase mutants G190S and G190A, which confer resistance to non-nucleoside reverse transcriptase inhibitors, demonstrate reductions in RNase H activity and DNA synthesis from tRNALys, 3 that correlate with reductions in replication efficiency

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The HIV-1 reverse transcriptase mutants G190S and G190A, which confer resistance to non-nucleoside reverse transcriptase inhibitors, demonstrate reductions in RNase H activity and DNA synthesis from tRNALys, 3 that correlate with reductions in replication efficiency

机译：HIV-1逆转录酶突变体G190S和G190A，其赋予非核苷逆转录酶抑制剂的抗性，证明了RNA酶H活性和从TRNARY的DNA合成的降低，3与复制效率的降低相关

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J. Wang; C. Dykes; R.A. Domaoal; C.E. Koval; R.A. Bambara; L.M. Demeter;
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1. The HIV-1 reverse transcriptase mutants G190S and G190A, which confer resistance to non-nucleoside reverse transcriptase inhibitors, demonstrate reductions in RNase H activity and DNA synthesis from tRNA(Lys,3) that correlate with reductions in replication efficiency [J] . Wang J., Dykes C., Domaoal R. A., Virology . 2006,第2期

机译：HIV-1逆转录酶突变体G190S和G190A赋予了非核苷逆转录酶抑制剂的抗性，证明RNase H活性的降低和tRNA（Lys，3）的DNA合成与复制效率的降低相关
2. The HIV-1 reverse transcriptase mutants G190S and G190A, which confer resistance to non-nucleoside reverse transcriptase inhibitors, demonstrate reductions in RNase H activity and DNA synthesis from tRNA(Lys, 3) that correlate with reductions in repl [J] . Wang J, Dykes C, Domaoal RA, Virology . 2006,第2期

机译：HIV-1逆转录酶突变体G190S和G190A赋予了对非核苷逆转录酶抑制剂的抗性，证明RNase H活性的降低和tRNA的DNA合成（Lys，3）与repl的降低有关
3. Alizarine derivatives as new dual inhibitors of the HIV-1 reverse transcriptase-associated DNA polymerase and RNase H activities effective also on the RNase H activity of non-nucleoside resistant reverse transcriptases [J] . Esposito Francesca, Kharlamova Tatyana, Distinto Simona, The FEBS journal . 2011,第9期

机译：茜素衍生物作为HIV-1逆转录酶相关DNA聚合酶和RNase H活性的新型双重抑制剂，对非核苷抗性逆转录酶的RNase H活性也有效
4. A Novel Detection of Non-nucleoside Reverse Transcriptase Inhibitors (NNRTIs) for HIV-1 with AlGaN/GaN High Electron Mobility Transistors [C] . Yen-Wen Kang, Geng-Yen Lee, Jen-Inn Chyi, Symposium on wide bandgap semiconductor materials and devices;Meeting of the Electrochemical Society . 2013

机译：AlGaN / GaN高电子迁移率晶体管对HIV-1的非核苷逆转录酶抑制剂（NNRTIs）的新型检测
5. Biochemical characterization of human immunodeficiency virus type 1 reverse transcriptase mutants to non-nucleoside reverse transcriptase inhibitors [D] . Domaoal, Robert A. 2005

机译：人类免疫缺陷病毒1型逆转录酶突变体对非核苷类逆转录酶抑制剂的生化特性
6. The HIV-1 reverse transcriptase mutants G190S and G190A which confer resistance to non-nucleoside reverse transcriptase inhibitors demonstrate reductions in RNase H activity and DNA synthesis from tRNALys3 that correlate with reductions in replication efficiency [O] . J. Wang, C. Dykes, R.A. Domaoal, -1

机译：HIV-1逆转录酶突变体G190S和G190A赋予了非核苷逆转录酶抑制剂的抗性证明RNase H活性降低和tRNALys合成DNA的减少3与复制效率的降低相关
7. Mutants of Human Immunodeficiency Virus Type 1 (HIV-1) Reverse Transcriptase Resistant to Nonnucleoside Reverse Transcriptase Inhibitors Demonstrate Altered Rates of RNase H Cleavage That Correlate with HIV-1 Replication Fitness in Cell Culture [O] . Archer, Richard H., Dykes, Carrie, Gerondelis, Peter, 2000

机译：抗非核苷类逆转录酶抑制剂的人类免疫缺陷病毒1型（HIV-1）逆转录酶突变体显示与细胞培养中HIV-1复制适应性相关的RNase H裂解率发生变化。

The HIV-1 reverse transcriptase mutants G190S and G190A, which confer resistance to non-nucleoside reverse transcriptase inhibitors, demonstrate reductions in RNase H activity and DNA synthesis from tRNALys, 3 that correlate with reductions in replication efficiency

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