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首页> 外文OA文献 >Improved dose-calculation accuracy in proton treatment planning using a simplified Monte Carlo method verified with three-dimensional measurements in an anthropomorphic phantom
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Improved dose-calculation accuracy in proton treatment planning using a simplified Monte Carlo method verified with three-dimensional measurements in an anthropomorphic phantom

机译：在拟人体模中使用三维测量验证的简化蒙特卡罗方法，改进了质子治疗计划中剂量计算的准确性

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摘要

Treatment planning for proton tumor therapy requires a fast and accurate dose-calculation method. We have implemented a simplified Monte Carlo (SMC) method in the treatment planning system of the National Cancer Center Hospital East for the double-scattering beam delivery scheme. The SMC method takes into account the scattering effect in materials more accurately than the pencil beam algorithm by tracking individual proton paths. We confirmed that the SMC method reproduced measured dose distributions in a heterogeneous slab phantom better than the pencil beam method. When applied to a complex anthropomorphic phantom, the SMC method reproduced the measured dose distribution well, satisfying an accuracy tolerance of 3 mm and 3% in the gamma index analysis. The SMC method required approximately 30 min to complete the calculation over a target volume of 500 cc, much less than the time required for the full Monte Carlo calculation. The SMC method is a candidate for a practical calculation technique with sufficient accuracy for clinical application.
机译：质子肿瘤治疗的治疗计划需要一种快速而准确的剂量计算方法。我们已经在东部国家癌症中心医院的治疗计划系统中实施了简化的蒙特卡洛（SMC）方法，以实现双散射束传输方案。 SMC方法通过跟踪各个质子路径，比笔形束算法更准确地考虑了材料中的散射效应。我们证实，SMC方法在异质平板模型中的测量剂量分布比铅笔束方法更好。当应用于复杂的拟人模型时，SMC方法可以很好地重现所测得的剂量分布，在伽玛指数分析中满足3 mm和3％的精度公差。 SMC方法大约需要30分钟才能完成目标体积500 cc的计算，这比完整的Monte Carlo计算所需的时间要少得多。 SMC方法是一种实用的计算技术的候选方法，该方法具有足够的临床准确性。

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