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The effect of general versus spinal anesthesia on blood sugar changesduring surgery

机译:全身麻醉与脊柱麻醉对手术过程中血糖变化的影响

摘要

Aim and Background: Stress of surgery transfers some neurological and hormonal signalsudwhich triggers some physiological responses like adrenergic stimulation, increase in noradrenalin,udcortisol, growth factor, decrease in insulin and increase in insulin resistance resultingudin hyperglycemia during surgery. In this study a comparison is done between general anesthesiaudwhich by blocking brain's signals decreases reactions to the stress of surgery and hyperglycemia,udand spinal analgesia which blocks hormonal and adrenergic reactions by peripheral effect.udMethods and Materials: This randomized control clinical trial study was performed on 60 ASAudI, II patients candidate of inguinal hernioraphy. The patients were randomly allocated to generaludanesthesia or spinal anesthesia with T12 level. Blood sugar of the patients was measured byudglucometer 1 hour before the surgery and 1 hour and 6 hours postoperatively.udFindings: There was no significant difference in blood sugar levels before the surgery betweenudtwo groups but it was lower 1and 6 hours postoperatively in spinal anesthesia group.udConclusions: Spinal analgesia more effectively controls rises in blood sugar during the surgery and mayudbe a suitable alternative for general anesthesia in patients with metabolic disorders.
机译:目的和背景:手术压力传递一些神经和激素信号,从而触发一些生理反应,如肾上腺素刺激,去甲肾上腺素,皮质醇,生长因子,胰岛素减少和胰岛素抵抗增加,从而导致 udin高血糖。在这项研究中,进行了全麻麻醉的比较,它通过阻断大脑的信号降低了对手术压力和高血糖的反应,而通过麻醉和脊髓镇痛通过外围作用来阻断激素和肾上腺素的反应。 ud方法和材料:该随机对照临床试验对60名ASA udI,II型腹股沟疝患者进行了研究。患者被随机分配至全麻或全麻或T12水平的脊髓麻醉。术前1小时,术后1小时和6小时通过血糖仪测量患者的血糖。 ud结果:两组患者术前血糖水平无显着差异,但术后1和6小时降低结论:脊柱镇痛可以在手术过程中更有效地控制血糖升高,并且可能是代谢紊乱患者全麻的合适替代方案。

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