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LncRNAWiki: harnessing community knowledge in collaborative curation of human long non-coding RNAs

机译：LncRNAWiki：利用社区知识共同管理人类长非编码RNA

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摘要

Long non-coding RNAs (lncRNAs) perform a diversity of functions in numerous important biological processes and are implicated in many human diseases. In this report we present lncRNAWiki (http://lncrna.big.ac.cn), a wiki-based platform that is open-content and publicly editable and aimed at community-based curation and collection of information on human lncRNAs. Current related databases are dependent primarily on curation by experts, making it laborious to annotate the exponentially accumulated information on lncRNAs, which inevitably requires collective efforts in community-based curation of lncRNAs. Unlike existing databases, lncRNAWiki features comprehensive integration of information on human lncRNAs obtained from multiple different resources and allows not only existing lncRNAs to be edited, updated and curated by different users but also the addition of newly identified lncRNAs by any user. It harnesses community collective knowledge in collecting, editing and annotating human lncRNAs and rewards community-curated efforts by providing explicit authorship based on quantified contributions. LncRNAWiki relies on the underling knowledge of scientific community for collective and collaborative curation of human lncRNAs and thus has the potential to serve as an up-to-date and comprehensive knowledgebase for human lncRNAs.
机译：长的非编码RNA（lncRNA）在许多重要的生物学过程中执行多种功能，并与许多人类疾病有关。在本报告中，我们介绍了lncRNAWiki（http://lncrna.big.ac.cn），这是一个基于Wiki的平台，该平台是开放内容且可公共编辑，旨在基于社区的策展和人类lncRNA信息的收集。当前相关的数据库主要依赖于专家的管理，这使得对lncRNA的指数积累信息进行注释变得费力，这不可避免地需要在基于社区的lncRNA的管理中进行集体努力。与现有数据库不同，lncRNAWiki具有对从多种不同资源获得的人类lncRNA的信息进行全面整合的功能，不仅允许现有的lncRNA由不同的用户进行编辑，更新和管理，而且还允许任何用户添加新识别的lncRNA。它利用社区集体知识来收集，编辑和注释人类lncRNA，并通过基于量化贡献提供明确的作者身份来奖励社区策划的工作。 LncRNAWiki依靠科学界的基础知识来进行人类lncRNA的集体和协作管理，因此有潜力作为人类lncRNA的最新和全面的知识库。

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