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Higher CNS penetration-effectiveness of long-term combination antiretroviral therapy is associated with better HIV-1 viral suppression in cerebrospinal fluid

机译：长期联合抗逆转录病毒疗法对中枢神经系统的穿透作用更高，与脑脊液中HIV-1病毒抑制效果更好相关

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To determine HIV-1 RNA in cerebrospinal fluid (CSF) of successfully treated patients and to evaluate if combination antiretroviral treatments with higher central nervous system penetration-effectiveness (CPE) achieve better CSF viral suppression.

机译：为了确定成功治疗的患者的脑脊液（CSF）中的HIV-1 RNA，并评估抗逆转录病毒疗法与中枢神经系统穿透效率（CPE）更高的组合是否能更好地抑制CSF病毒。

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Cusini Alexia; Vernazza Pietro L; Yerly Ferrillo Sabine; Decosterd Laurent A; Ledergerber Bruno; Fux Christoph A; Rohrbach Janine; Widmer Nicolas; Hirschel Bernard; Gaudenz Roman; Cavassini Matthias; Klimkait Thomas; Zenger Franziska; Gutmann Chistine; Opravil Milos; Günthard Huldyrich F;
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1. Higher CNS penetration-effectiveness of long-term combination antiretroviral therapy is associated with better hiv-1 viral suppression in cerebrospinal fluid [J] . JAIDS: Journal of acquired immune deficiency syndromes . 2013,第1期

机译：长期联合抗逆转录病毒疗法对中枢神经系统的穿透作用较高，与脑脊液中更好的HIV-1病毒抑制作用有关
2. Asymptomatic Cerebrospinal Fluid HIV-1 Viral Blips and Viral Escape During Antiretroviral Therapy: A Longitudinal Study [J] . Eden Arvid, Nilsson Staffan, Hagberg Lars, The Journal of Infectious Diseases . 2016,第12期

机译：抗逆转录病毒疗法过程中无症状的脑脊髓液HIV-1病毒斑点和病毒逸出：纵向研究。
3. Cerebrospinal fluid drug concentrations and viral suppression in HIV-1-infected patients receiving ritonavir-boosted atazanavir plus lamivudine dual antiretroviral therapy (Spanish HIV/AIDS Research Network, PreEC/RIS 39) [J] . Arkaitz Imaz, Jordi Niubó, Alieu Amara, Journal of neurovirology . 2018,第4期

机译：脑脊液液体浓度和病毒抑制在HIV-1感染患者中接受Ritonavir-Boosted Atazanavir Plus Lamivudine双抗逆转录病毒治疗（西班牙艾滋病毒/艾滋病研究网络，Prec / Ris 39）
4. Could low level laser therapy and highly active antiretroviral therapy lead to complete eradication of HIV-1 in vitro? [C] . Masixole Yvonne Lugongolo, Sello Lebohang Manoto, Saturnin Ombinda-Lemboumba, Biophysics, Biology and Biophotonics II: the Crossroads . 2017

机译：低水平激光疗法和高活性抗逆转录病毒疗法能否导致在体外完全消除HIV-1？
5. CD4+ T Cell Recovery and Cerebrospinal Fluid Escape After Antiretroviral Therapy Initiation in Acute HIV-1 Infection [D] . ?Handoko, Ryan Christopher 2020

机译：CD4 + T 细胞回收和急性 HIV-1 感染脑脊液逃逸抗逆转录病毒疗法开始后
6. Cost-Effectiveness Analysis of Lopinavir/Ritonavir Monotherapy Versus Standard Combination Antiretroviral Therapy in HIV-1 Infected Patients with Viral Suppression in France (ANRS 140 DREAM) [O] . Osvaldo Ulises Garay, Marie Libérée Nishimwe, Marwân-al-Qays Bousmah, 2019

机译：法国对罗非那韦/利托那韦单药治疗与标准联合抗逆转录病毒疗法对HIV-1感染的病毒抑制患者的成本效果分析（ANRS 140 DREAM）
7. Higher CNS Penetration-Effectiveness of long-term combination antiretroviral therapy is associated with better HIV-1 viral suppression in cerebrospinal fluid [O] . Cusini A, Vernazza P L, Yerly S, 2013

机译：长期联合抗逆转录病毒疗法对中枢神经系统的穿透作用更高，与脑脊液中HIV-1病毒抑制效果更好相关

Higher CNS penetration-effectiveness of long-term combination antiretroviral therapy is associated with better HIV-1 viral suppression in cerebrospinal fluid

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