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首页> 外文OA文献 >An investigation of the performance of a new Mechanical thrombectomy device using Bond Graph modelling: application to the extraction of blood clots in the middle cerebral artery
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An investigation of the performance of a new Mechanical thrombectomy device using Bond Graph modelling: application to the extraction of blood clots in the middle cerebral artery

机译：使用Bond Graph建模技术研究新型机械血栓切除术设备的性能：在脑中动脉血栓提取中的应用

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摘要

A number of thrombectomy devices using a variety of methods have now been developed to facilitate clot removal. We present research involving one such experimental device recently developed in the UK, called a ‘GP’ Thrombus Aspiration Device (GPTAD). This device has the potential to bring about the extraction of a thrombus. Although the device is at a relatively early stage of development, the results look encouraging. In this work, we present an analysis and modeling of the GPTAD by means of the bond graph technique; it seems to be a highly effective method of simulating the device under a variety of conditions. Such modeling is useful in optimizing the GPTAD and predicting the result of clot extraction. The aim of this simulation model is to obtain the minimum pressure necessary to extract the clot and to verify that both the pressure and the time required to complete the clot extraction are realistic for use in clinical situations, and are consistent with any experimentally obtained data. We therefore consider aspects of rheology and mechanics in our modeling.
机译：现在已经开发出使用各种方法的许多血栓切除术设备以促进血块去除。我们目前的研究涉及最近在英国开发的一种这样的实验装置，称为“ GP”血栓抽吸装置（GPTAD）。该装置具有引起血栓抽出的潜力。尽管该设备处于开发的相对早期阶段，但结果看起来令人鼓舞。在这项工作中，我们将通过键图技术对GPTAD进行分析和建模。它似乎是在多种条件下模拟设备的高效方法。这种模型可用于优化GPTAD和预测血块提取结果。该模拟模型的目的是获得提取凝块所需的最小压力，并验证完成凝块提取所需的压力和时间对于在临床情况下使用是现实的，并且与任何实验获得的数据一致。因此，我们在建模时会考虑流变学和力学方面。

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