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Human Thiel-Embalmed Cadaveric Aortic Model with Perfusion for Endovascular Intervention Training and Medical Device Evaluation

机译：人Thiel-Embalmed动脉导管灌注模型用于血管内介入训练和医疗器械评估

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: The purpose of this investigation was to evaluate human Thiel-embalmed cadavers with the addition of extracorporeal driven ante-grade pulsatile flow in the aorta as a model for simulation training in interventional techniques and endovascular device testing.: Three human cadavers embalmed according to the method of Thiel were selected. Extracorporeal pulsatile ante-grade flow of 2.5 L per min was delivered directly into the aorta of the cadavers via a surgically placed connection. During perfusion, aortic pressure and temperature were recorded and optimized for physiologically similar parameters. Pre- and post-procedure CT imaging was conducted to plan and follow up thoracic and abdominal endovascular aortic repair as it would be in a clinical scenario. Thoracic endovascular aortic repair (TEVAR) and endovascular abdominal repair (EVAR) procedures were conducted in simulation of a clinical case, under fluoroscopic guidance with a multidisciplinary team present.: The Thiel cadaveric aortic perfusion model provided pulsatile ante-grade flow, with pressure and temperature, sufficient to conduct a realistic simulation of TEVAR and EVAR procedures. Fluoroscopic imaging provided guidance during the intervention. Pre- and post-procedure CT imaging facilitated planning and follow-up evaluation of the procedure.: The human Thiel-embalmed cadavers with the addition of extracorporeal flow within the aorta offer an anatomically appropriate, physiologically similar robust model to simulate aortic endovascular procedures, with potential applications in interventional radiology training and medical device testing as a pre-clinical model.
机译：：这项研究的目的是评估人类Thiel胸膜尸体，并在主动脉中添加体外驱动的前级脉动血流，作为干预技术和血管内装置测试的模拟训练模型。：三只尸体根据选择了泰尔的方法。每分钟2.5 L的体外搏动前流通过外科手术连接直接输送到尸体的主动脉中。在灌注过程中，记录主动脉压力和温度并针对生理上相似的参数进行优化。进行术前和术后CT成像以计划和随访胸腔和腹部血管内主动脉修复，就像在临床情况下一样。在临床案例的模拟下，在荧光检查的指导下，在多学科团队的指导下，进行了胸腔内血管主动脉修复（TEVAR）和血管内腹腔修复（EVAR）程序。：Thiel尸体主动脉灌注模型可提供脉动前级血流，压力和温度，足以对TEVAR和EVAR程序进行逼真的仿真。荧光镜检查在干预过程中提供了指导。术前和术后CT成像有助于对手术进行计划和后续评估。：在主动脉内增加了体外血流的人类蒂尔族尸体提供了解剖学上合适的，生理上相似的健壮模型来模拟主动脉腔内手术，具有作为临床前模型在介入放射学培训和医疗设备测试中的潜在应用。

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