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A pilot case series of a brief Acceptance and Commitment Therapy (ACT)-based guided self-help intervention for improving quality of life and mood in muscle disorders

机译:一个简短的基于接受和承诺疗法(ACT)的指导性自助干预的试验案例系列,旨在改善肌肉疾病的生活和情绪

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摘要

This study aimed to demonstrate proof of concept and acceptability of a brief Acceptance and Commitment Therapy (ACT)-based guided self-help intervention for improving quality of life (QoL) and mood for people with muscle disorders (MD). A case-series with an AB design was used to assess changes in primary (QoL) and secondary (depression and anxiety) outcome variables across the period of study. Change in the psychological process targeted by ACT - psychological flexibility – was also investigated, to allow some insight into possible treatment mechanisms. Post-intervention, participants also completed a brief free-text evaluation. Relative to pre-intervention scores, four (of seven) participants showed varying degrees of improvement in all primary and secondary outcome variables and were thus considered responders. However, consistent concomitant improvements in psychological flexibility were not apparent. Participants reported a mostly positive experience of the intervention; all appeared to complete the intervention, and no adverse events were reported. Nonetheless, there was evidence that those with compromised concentration or who report good initial QoL and low levels of distress may derive less benefit. Although several methodological weaknesses limit the strength of our conclusions, this ACT-based guided self-help intervention shows encouraging utility for improving QoL and mood in MD.
机译:这项研究旨在证明基于简短的基于接受和承诺疗法(ACT)的指导性自助干预措施的概念和可接受性证明,以改善肌肉疾病(MD)患者的生活质量(QoL)和情绪。采用AB设计的案例系列用于评估研究期间主要(QoL)和次要(抑郁和焦虑)结果变量的变化。还研究了以ACT为目标的心理过程的变化-心理灵活性-以便对可能的治疗机制有一些了解。干预后,参与者还完成了简短的自由文本评估。相对于干预前的分数,四名参与者(七名参与者)在所有主要和次要结果变量中均有不同程度的改善,因此被认为是有反应的。然而,心理灵活性的持续伴随改善尚不明显。与会者报告说,该干预措施基本上是积极的。似乎都完成了干预,没有不良反应的报道。尽管如此,有证据表明,那些注意力不集中或报告良好的初始QoL和低困扰水平的人可能会获得较少的收益。尽管一些方法上的弱点限制了我们结论的强度,但是这种基于ACT的指导性自助干预显示出令人鼓舞的效用,可改善MD的QoL和情绪。

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