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Stable absolute flow estimation with Doppler OCT based on virtual circumpapillary scans

机译:多普勒OCT基于虚拟乳头周向扫描的绝对流量估计稳定

摘要

Doppler optical coherence tomography has the capability to measure blood flow quantitatively and in vivo. As only the axial component of the velocity can be assessed, the measurements have to be corrected for the angle of the vessels. We present a novel approach to extract quantitative flow data from circumpapillary scans in vivo on the human retina by registering the circular scan to a reference volume scan and extracting the angle directly from the volume. In addition, we perform phase unwrapping and interpolation of the flow under the assumption of a parabolic flow profile. We demonstrate the repeatability of the methods by applying it to different retinal vessels, achieving coefficients of variation of the average velocity of 3 to 8%. Results on the pulsatility and resistance index are also presented.
机译:多普勒光学相干断层扫描具有定量和体内测量血流的能力。由于只能评估速度的轴向分量,因此必须针对血管角度校正测量值。我们提出了一种新颖的方法,可通过将圆形扫描注册到参考体积扫描并直接从体积中提取角度,从人体视网膜上的乳头环周扫描中提取定量流量数据。此外,我们在抛物线流动剖面的假设下执行相位展开和插值。我们通过将其应用于不同的视网膜血管,实现了3%至8%的平均速度变化系数,证明了该方法的可重复性。还介绍了搏动性和阻力指数的结果。

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