The effects of aberrations on image quality and theudobjectively assessed (DoF) were studied. Aberrometry data from 80 young subjects with a range of refractive errors was used for computing the (VSOTF), and then, through-focus simulations were performed in order to calculate the objective DoF (using two different relative thresholds of 50% and 80%; andudtwo different pupil diameters) and the image quality (theudpeak VSOTF). Both lower order astigmatism and (HOA) terms up to the fifth radial order were considered. The results revealed that, of the HOAs, the comatic terms (third and fifth order) explained most of the variations of the DoF and the image quality in this population of subjects. Furthermore, computerudsimulations demonstrated that the removal of theseudterms also had a significant impact on both DoF and theudpeak VSOTF. Knowledge about the relationship betweenudaberrations, DoF, image quality, and their interactions isudessential in optical designs aiming to produce largeudvalues of DoF while maintaining an acceptable level ofudimage quality. Comatic aberration terms appear toudcontribute strongly towards the configuration of both ofudthese visually important parameters.
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