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Aggrecan fragments in the synovial fluid of osteoarthritis and juvenile idiopathic arthritis patients reveals differences in the specificity of aggrecanase cleavage in the interglobular domain, but not in the chondroitin-sulphate-rich region

机译：骨关节炎和幼年特发性关节炎患者滑膜液中的Aggrecan碎片显示球蛋白域中软骨聚集蛋白聚糖酶裂解的特异性差异，而富含硫酸软骨素的区域则没有

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Struglics A.; Lohmander S.; Last K.; Allen R.; Fosang A.J.;
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1. Aggrecanase cleavage in juvenile idiopathic arthritis patients is minimally detected in the aggrecan interglobular domain but robust at the aggrecan C-terminus [J] . StruglicsA., LohmanderL.S., LastK., Arthritis and Rheumatism . 2012,第12期

机译：在聚集蛋白聚糖球状结构域中极少检测到幼年特发性关节炎患者的Aggrecanase裂解，但在聚集蛋白聚糖C末端具有很强的抵抗力
2. Human osteoarthritis synovial fluid and joint cartilage contain both aggrecanase- and matrix metalloproteinase-generated aggrecan fragments. [J] . Struglics A, Larsson S, Pratta MA, Osteoarthritis and cartilage . 2006,第2期

机译：人骨关节炎滑液和关节软骨均含有软骨聚集蛋白聚糖酶和基质金属蛋白酶生成的软骨聚集蛋白聚糖片段。
3. DEVELOPMENT OF A CLEAVAGE-SITE-SPECIFIC MONOCLONAL ANTIBODY FOR DETECTING METALLOPROTEINASE-DERIVED AGGRECAN FRAGMENTS - DETECTION OF FRAGMENTS IN HUMAN SYNOVIAL FLUIDS [J] . Fosang AJ, Last K, Gardiner P, The Biochemical Journal . 1995,第0期

机译：用于检测金属蛋白酶衍生的希腊片段的卵裂位特异性单克隆抗体的开发-检测人类滑液中的片段
4. CD137 and CD137 ligand and its soluble forms in plasma and synovial fluid from patients with juvenile idiopathic arthritis [C] . Stiefel M., Muller T. G., Huhn R., European Congress of Immunology . 2009

机译：CD137和CD137配体及其来自幼年特发性关节炎患者的血浆和滑膜中的可溶性形式
5. The structure of aggrecan fragments in human synovial fluid. Evidence for the involvement in osteoarthritis of a novel proteinase which cleaves the Glu 373-Ala 374 bond of the interglobular domain. [O] . J D Sandy, C R Flannery, P J Neame, 1992

机译：人滑液中聚集蛋白聚糖片段的结构。新颖的蛋白酶参与球状结构域的Glu 373-Ala 374键断裂的证据涉及骨关节炎。
6. Aggrecanase Cleavage in Juvenile Idiopathic Arthritis Patients Is Minimally Detected in the Aggrecan Interglobular Domain but Robust at the Aggrecan C-Terminus [O] . Struglics, André, Lohmander, Stefan, Last, Karena, 2012

机译：少发性特发性关节炎患者中的Aggrecanase卵裂在Aggrecan球间域中的检出率最低，但在Aggrecan C端的作用稳定

Aggrecan fragments in the synovial fluid of osteoarthritis and juvenile idiopathic arthritis patients reveals differences in the specificity of aggrecanase cleavage in the interglobular domain, but not in the chondroitin-sulphate-rich region

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