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Inter-firm RD networks in the global pharmaceutical biotechnology industry during 1985?1998 : a conceptual and empirical analysis

机译：1985？1998年间全球制药生物技术行业的公司间研发网络：概念和实证分析

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摘要

This paper analyses a large database on inter-firm R&D cooperation formed in the pharmaceutical biotechnology industry during the period 1985?1998. The results indicate that network size largely grows, whereas the density of the network declines during the periods. In the network analysis that emphasizes individual structural positions, the empirical results show that small biotechnological companies had a crucial bridging role for the large pharmaceutical firms in the second half of the 1980s. In the 1990s, the bridge role of biotechnology companies became less important and established pharmaceutical companies developed into dominant start players with many collaborators while holding central roles in the research network. The current analysis also shows that degree-based and betweenness-based network centralization are both low implying that the overall positional advantages are relatively equally distributed in the inter-firm R&D network of the pharmaceutical biotechnology industry.
机译：本文分析了一个大型数据库，该数据库涉及1985年至1998年间在制药生物技术行业中形成的企业间研发合作。结果表明，网络规模在此期间大幅增长，而网络密度在下降。在强调个体结构位置的网络分析中，经验结果表明，小型生物技术公司在大型制药公司中扮演着重要的桥梁角色，在1980年代下半年。在1990年代，生物技术公司的桥梁作用变得不那么重要了，成熟的制药公司发展成为具有许多合作者的主导起步者，同时在研究网络中发挥了核心作用。当前的分析还表明，基于程度和基于中间性的网络集中度都较低，这意味着总体位置优势在制药生物技术行业的公司间研发网络中相对平均地分布。

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