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METHOD OF LIFE-TIME MICROSTRUCTURE EVALUATION OF TUMOUR TISSUE IN EXPERIMENT

机译：实验性肿瘤组织生命周期微观评价方法

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摘要

FIELD: medicine.;SUBSTANCE: invention relates to experimental medicine and can be used for lifetime assessment of microstructure of tumour tissue in experiment. Elastographic examination is performed in the tumour centre, during which OCE-images are obtained. Obtained images are analysed. That is followed by segmentation of OCE images, selecting viable tumour cells with stiffness ranging from 621 to 2000 kPa, dystrophic tumour cells with stiffness ranging from 411 to 620 kPa, oedema of tumour tissue with rigidity in range from 231 to 410 kPa, necrosis of tumour tissue with rigidity in range from 100 to 230 kPa. Area of segments relative to the total area of the OCE-image is calculated.;EFFECT: method provides higher accuracy of assessing detection of various microstructures of the tumour, eliminating subjectivity and quantitative assessment of microstructure of tissue in the area of interest by determining quantitative indicators of stiffness of tumour tissue.;1 cl, 3 dwg, 3 ex

机译：技术领域本发明涉及实验医学，可用于实验中肿瘤组织微观结构的终生评估。在肿瘤中心进行弹性成像检查，在此期间获得OCE图像。对获得的图像进行分析。随后进行OCE图像分割，选择硬度在621至2000 kPa范围内的存活肿瘤细胞，营养不良的硬度在411至620 kPa范围内的肿瘤细胞，硬度在231至410 kPa范围内的肿瘤组织水肿，坏死肿瘤组织的刚性范围为100至230 kPa。计算相对于OCE图像总面积的节段面积。效果：该方法提供了更高的评估评估各种肿瘤微结构检测的准确性，消除了主观判断，并通过确定定量来定量评估感兴趣区域组织的微结构肿瘤组织刚度的指标。; 1 cl，3 dwg，3 ex

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公开/公告号RU2732823C1

专利类型
公开/公告日2020-09-22

原文格式PDF
申请/专利权人 FEDERAL STATE BUDGETARY EDUCATIONAL INSTITUTION OF HIGHER EDUCATION PRIVOLZHSKY RESEARCH MEDICAL UNIVERSITY OF THE MINISTRY OF HEALTH OF THE RUSSIAN FEDERATION (FSBEI HE PRMU MOH RUSSIA);
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申请/专利号RU20200114397
发明设计人 PLEKHANOV ANTON ANDREEVICH (RU);SIROTKINA MARINA ALEKSANDROVNA (RU);GUBARKOVA EKATERINA VLADIMIROVNA (RU);ZAJTSEV VLADIMIR YUREVICH (RU);SOVETSKIJ ALEKSANDR ALEKSANDROVICH (RU);KUZNETSOV SERGEJ STANISLAVOVICH (RU);MATVEEV LEV ALEKSANDROVICH (RU);MATVEEV ALEKSANDR LVOVICH (RU);ZAGAJNOVA ELENA VADIMOVNA (RU);GLADKOVA NATALYA DOROFEEVNA (RU);
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申请日2020-04-22
分类号G09B23/28;
国家 RU
入库时间 2022-08-21 11:02:15

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