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METHOD FOR PREDICTION OF OVERALL SURVIVAL OF MALE PATIENTS WITH CHRONIC LYMPHATIC LEUKEMIA IN STAGE A-C

机译:预测A-C期慢性淋巴白血病的男性患者总生存率的方法

摘要

FIELD: medicine.;SUBSTANCE: invention refers to medicine, particularly to oncohematology. Described is a method for prediction of total survival of the male patients with chronic lymphatic leukemia (CLL) at stage A-C according to Binet. A glomerular filtration rate (GFR) of the patient is determined by MDRD formula: GFR=186×{[serum (plasma) creatinine+88.4]-1.154}×age-0.0203. To increase the patient's predicted clinical parameters of the median of the Binet classification, the following formula is introduced: L=X-76.5, where X is the patient's GFR parameter at the moment of diagnosis, wherein in the case of L≥0 – patient will overcome median of Binet classification, at L0 – patient will not overcome median of Binet classification.;EFFECT: more accurate prediction of overall survival of CLL patients.;1 cl, 2 tbl, 3 ex
机译:技术领域:发明涉及医学,尤其是肿瘤血液学。根据Binet,本文描述了一种预测A-C期慢性淋巴白血病(CLL)男性患者总生存的方法。通过MDRD公式确定患者的肾小球滤过率(GFR):GFR = 186×{[血清(血浆)肌酐+88.4] -1.154 }×age -0.0203 。为了增加患者的Binet分类中位数的预测临床参数,引入以下公式:L = X-76.5,其中X是诊断时患者的GFR参数,其中L≥0时–患者将克服Binet分类的中位数,在L <0时–患者将不会克服Binet分类的中位数。;效果:更准确地预测CLL患者的总体生存率。; 1 cl,2 tbl,3 ex

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