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METHOD FOR SIMULATING AN INTRA-ABDOMINAL PSEUDOMONAS INFECTION PROCESS

机译：模拟腹内假单胞菌感染过程的方法

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摘要

FIELD: microbiology.;SUBSTANCE: invention relates to microbiology and can be used to develop therapeutic measures to suppress infection caused by antibiotic-resistant Pseudomonas aeruginosa strains. Disclosed is a method for simulating an intraperitoneal Pseudomonas infection process, involving intraperitoneal introduction of a daily suspension of Pseudomonas aeruginosa culture. Pseudomonas aeruginosa culture is obtained by washing off with a solid nutrient medium 0.85 % physiologic saline, wherein the introduced rabbit culture volume is 2 ml, concentration in 1 ml is increased to 10⁸ microbial cells according to Tarasevich's turbidity standard in a sterile test tube; clinical signs of infection are observed 24–32 hours after Pseudomonas aeruginosa introduction.;EFFECT: invention provides creating technically simple and highly reproducible model of intraperitoneal Pseudomonas infectious process.;1 cl, 5 dwg, 3 ex

机译：铜假单胞菌铜绿假单胞菌菌株引起的感染的治疗方法技术领域本发明涉及微生物学，并且可以用于开发治疗措施以抑制由耐药性铜绿假单胞菌菌株引起的感染。公开了一种模拟腹膜内假单胞菌感染过程的方法，该方法涉及腹膜内引入铜绿假单胞菌培养物的每日悬浮液。铜绿假单胞菌培养物是通过用0.85％的生理食盐水冲洗掉而获得的，其中引入的兔培养物体积为2 ml，根据Tarasevich的浊度将1 ml中的浓度增加到10 ^{8 微生物细胞无菌试管中的标准液;引入铜绿假单胞菌后24-32小时观察到感染的临床体征。效果：本发明提供了技术上简单且可重现的腹膜内假单胞菌感染过程模型。1cl，5 dwg，3 ex}

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公开/公告号RU2725136C1

专利类型
公开/公告日2020-06-30

原文格式PDF
申请/专利权人 FEDERALNOE GOSUDARSTVENNOE BYUDZHETNOE OBRAZOVATELNOE UCHREZHDENIE VYSSHEGO OBRAZOVANIYA STAVROPOLSKIJ GOSUDARSTVENNYJ AGRARNYJ UNIVERSITET;
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申请/专利号RU20190137642
发明设计人 SHAKHOVA VALERIYA NIKOLAEVNA (RU);BELYAEV VALERIJ ANATOLEVICH (RU);SVETLAKOVA ELENA VALENTINOVNA (RU);KASTARNOVA ELENA SERGEEVNA (RU);ZINCHENKO DMITRIJ ALEKSEEVICH (RU);
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申请日2019-11-21
分类号G09B23/28;C12Q1/02;
国家 RU
入库时间 2022-08-21 11:02:27

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