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首页> 外国专利> METHOD FOR ASSESSING THE DEVELOPMENTAL PREDICTION IN CHILDREN DIAGNOSED WITH BRONCHIAL ASTHMA ACCOMPANYING A COMORBID PATHOLOGY IN THE FORM OF AN AUTONOMIC NERVOUS SYSTEM DISORDER AND A FUNCTIONAL PATHOLOGY OF THE GASTROINTESTINAL TRACT IN CONDITIONS OF MULTI-COMPONENT CONTAMINATION OF ATMOSPHERIC AIR WITH SUSPENDED SUBSTANCES, NITROGEN DIOXIDE AND ORGANIC AROMATIC COMPOUNDS IN THE TERRITORY WHERE CHILDREN LIVE

METHOD FOR ASSESSING THE DEVELOPMENTAL PREDICTION IN CHILDREN DIAGNOSED WITH BRONCHIAL ASTHMA ACCOMPANYING A COMORBID PATHOLOGY IN THE FORM OF AN AUTONOMIC NERVOUS SYSTEM DISORDER AND A FUNCTIONAL PATHOLOGY OF THE GASTROINTESTINAL TRACT IN CONDITIONS OF MULTI-COMPONENT CONTAMINATION OF ATMOSPHERIC AIR WITH SUSPENDED SUBSTANCES, NITROGEN DIOXIDE AND ORGANIC AROMATIC COMPOUNDS IN THE TERRITORY WHERE CHILDREN LIVE

机译：评估患有支气管哮喘的儿童的发展预测，伴有自发性神经系统疾病的合并神经病理紊乱和功能性肠胃病的病理性病变，并伴有多种内容物的含硫量儿童居住的领土上的有机芳香化合物

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摘要

FIELD: medicine.;SUBSTANCE: invention relates to medicine, namely to a method for assessing the developmental prediction in children diagnosed with bronchial asthma, accompanying comorbid pathology in the form of a vegetative nervous system disorder and functional pathology of the gastrointestinal tract in conditions of multi-component contamination of atmospheric air with suspended substances, nitrogen dioxide and organic aromatic compounds in the territory where children live. Method comprises determining a blood sample content of organic aromatic compounds: benzene, toluene, phenol, formaldehyde, and in atmosphere of territory, where children live, – content of suspended particles and nitrogen dioxide, and if they exceed the reference number by at least 1.5 times, laboratory and functional values are determined, wherein the laboratory values are determined by the level of creatine phosphokinase and ionized calcium in blood, functional indicators are systolic pulmonary arterial pressure (SPAP), ratio of stress index in wedge-orthostatic sample to initial stress index (IN2/IN1), and if the creatinine phosphokinase level is higher than 209 E/dm3, the level of ionized calcium in blood exceeds 1.21 mmol/l, the SPAP level is more than 20 mm Hg, the IN2/IN1 level is more than 3.3 standard units, the comorbid pathology prognosis development accompanying bronchial asthma is estimated in the form of vegetative nervous system disorder and functional pathology of the gastrointestinal tract associated with negative aerogenic effect of suspended substances, nitrogen dioxide and organic aromatic compounds, as high.;EFFECT: invention enables creating an informative and evidence-based method of predicting development in children diagnosed with bronchial asthma, accompanying comorbid pathology in the form of a vegetative nervous system disorder and functional pathology of the gastrointestinal tract, associated with the effect of organic aromatic compounds and suspended particles, nitrogen dioxide ingested by children from atmospheric air.;1 cl, 6 tbl, 2 ex
机译：技术领域本发明涉及医学，即一种用于评估诊断为支气管哮喘的儿童的发育预测的方法，该疾病伴有植物神经系统疾病形式的合并疾病和胃肠道功能性病理。在儿童居住地区，大气中的悬浮物，二氧化氮和有机芳香化合物受到多组分污染。方法包括确定血液样本中有机芳香化合物的含量：苯，甲苯，苯酚，甲醛，以及儿童所居住的地区的大气中，–悬浮颗粒和二氧化氮的含量，以及它们是否超过参考值至少1.5倍确定时间，实验室和功能值，其中实验室值由血液中的肌酸磷酸激酶和离子钙水平确定，功能指标是收缩期肺动脉压（SPAP），楔形立位样品中应力指数与初始应力之比指数（IN2 / IN1），如果肌酸酐磷酸激酶水平高于209 E / dm 3 ，则血液中离子钙的水平超过1.21 mmol / l，SPAP水平将超过20 mm汞，IN2 / IN1水平超过3.3个标准单位，伴有支气管哮喘的病理合并症预后发展以植物性神经系统疾病和功能性病变的形式进行估计胃肠道热与悬浮物，二氧化氮和有机芳香化合物的负气源作用有关;效果：发明创造了一种基于信息和循证的方法来预测诊断为支气管哮喘的儿童的发展，并伴有共病以营养神经系统疾病和胃肠道功能病理的形式出现，与有机芳香化合物和悬浮颗粒，儿童从大气中摄入的二氧化氮有关。1cl，6 tbl，2 ex

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