首页> 外国专利> METHOD FOR LYOPHILIC DRYING OF ATTENUATED BACTERIA B.PERTUSSIS, ATTENUATED BACTERIA B. PERTUSSIS, STRAIN OF ATTENUATED B. PERTUSSIS BACTERIA, VACCINE, LYOPHILIZED VACCINE PREPARATION

METHOD FOR LYOPHILIC DRYING OF ATTENUATED BACTERIA B.PERTUSSIS, ATTENUATED BACTERIA B. PERTUSSIS, STRAIN OF ATTENUATED B. PERTUSSIS BACTERIA, VACCINE, LYOPHILIZED VACCINE PREPARATION

机译：弱化枯草芽孢杆菌，弱化细菌B.百日咳，弱化枯草芽孢杆菌的菌株的亲液干燥方法，疫苗，冻干疫苗的制备

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FIELD: biotechnology.;SUBSTANCE: invention relates to biotechnology, particularly to attenuated Bordetella pertussis bacteria, which contains mutations in the regulatory and coding regions of the operon ptx and the coding region of the dnt gene, for use as a pertussis vaccine. Invention also discloses a strain of attenuated Bordetella pertussis bacteria, a lyophilized preparation thereof, a lyophilisation method thereof and a Bordetella pertussis bacteria vaccine.;EFFECT: invention solves the task of lyophilic drying of attenuated Bordetella pertussis bacteria, which enables to obtain live pertussis vaccines.;6 cl, 4 ex, 1 dwg, 6 tbl

机译：百日咳博德特氏菌减毒细菌技术领域本发明涉及生物技术，尤其涉及减毒的百日咳博德特氏菌，其在操纵子ptx的调节和编码区以及dnt基因的编码区中含有突变，用作百日咳疫苗。本发明还公开了一种减毒的百日咳博德特氏菌菌株，其冻干制剂，冻干方法和百日咳博德特氏菌疫苗。效果：本发明解决了减毒的百日咳博德特氏菌冻干的任务，从而可以得到活的百日咳疫苗。。; 6 cl，4 ex，1 dwg，6 tbl

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公开/公告号RU2709657C2

专利类型
公开/公告日2019-12-19

原文格式PDF
申请/专利权人 FEDERALNOE GOSUDARSTVENNOE BYUDZHETNOE UCHREZHDENIE NATSIONALNYJ ISSLEDOVATELSKIJ TSENTR EPIDEMIOLOGII I MIKROBIOLOGII IMENI POCHETNOGO AKADEMIKA N.F. GAMALEI MINISTERSTVA ZDRAVOOKHRANENIYA ROSSIJSKOJ FEDERATSII (FGBU NITSEM IM. N.F. GAMALEI MINZDRAVA ROSSII);
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申请/专利号RU20170128106
发明设计人 KARATAEV GENNADIJ IVANOVICH (RU);SINYASHINA LYUDMILA NIKOLAEVNA (RU);SEMIN EVGENIJ GRIGOREVICH (RU);MEDKOVA ALISA YUREVNA (RU);GINTSBURG ALEKSANDR LEONIDOVICH (RU);
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申请日2017-08-07
分类号C12N1/20;A61K39/10;C12N15/31;
国家 RU
入库时间 2022-08-21 11:02:44

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