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METHOD FOR PREVENTING ISCHEMIC AND REPERFUSION INJURIES OF THE HIPPOCAMPUS NEURONS IN THE POSTRESUSCITATIVE PERIOD

机译：术后恢复期预防海马神经元缺血和再灌注损伤的方法

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FIELD: medicine.;SUBSTANCE: declared invention refers to medicine and represents a method for prevention of ischemic and reperfusion injuries of the hippocampus neurons in the postresuscitative period, involving the use of lithium salts, characterized by that as an agent for preventing ischemic and reperfusion injuries of the hippocampus neonones in the postresuscitative period, 4.2 % lithium chloride solution is used in dose of 40 mg/kg by single intravenous introduction immediately after recovery of spontaneous cardiac activity and subsequent introduction on 1st, 2nd and 3rd post-intensive day.;EFFECT: use of the declared invention enables to neutralize consequences of both neuron ischemia and pathogenic extracerebral factors occurring in generalized reperfusion conditions.;1 cl, 3 dwg, 1 ex

机译：领域：公开的发明是指药物，并且代表一种预防在复苏后期海马神经元缺血和再灌注损伤的方法，该方法涉及使用锂盐，其特征在于作为预防缺血和再灌注的试剂复苏后的海马新生神经损伤，在自发心脏活动恢复后立即进行单次静脉内注射，然后以40 mg / kg的剂量使用4.2％氯化锂溶液，随后在强化后的第一，第二和第三天进行注射。效果：使用声明的发明能够中和在普遍的再灌注条件下发生的神经元缺血和病原性脑外因素的后果。1cl，3 dwg，1 ex

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公开/公告号RU2707875C1

专利类型
公开/公告日2019-12-02

原文格式PDF
申请/专利权人 FEDERALNOE GOSUDARSTVENNOE BYUDZHETNOE NAUCHNOE UCHREZHDENIE FEDERALNYJ NAUCHNO-KLINICHESKIJ TSENTR REANIMATOLOGII I REABILITOLOGII (FNKTS RR);
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申请/专利号RU20190114508
发明设计人 GREBENCHIKOV OLEG ALEKSANDROVICH (RU);OSTROVA IRINA VASILEVNA (RU);SHABANOV ASLAN KURBANOVICH (RU);MOLCHANOV IGOR VLADIMIROVICH (RU);KUZOVLEV ARTEM NIKOLAEVICH (RU);ERSHOV ANTON VALEREVICH (RU);LIKHVANTSEV VALERIJ VLADIMIROVICH (RU);GRECHKO ANDREJ VYACHESLAVOVICH (RU);
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申请日2019-05-14
分类号A61K33/14;A61P25;
国家 RU
入库时间 2022-08-21 11:02:47

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