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COMPOSITION FOR IMMUNOSTAINING OF CLEARED HUGE BIOLOGICAL TISSUE AND IMMUNOSTAINING METHOD FOR CLEARED HUGE TISSUE
COMPOSITION FOR IMMUNOSTAINING OF CLEARED HUGE BIOLOGICAL TISSUE AND IMMUNOSTAINING METHOD FOR CLEARED HUGE TISSUE
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机译:清除巨大生物组织的免疫抑制的组合物和清除巨大组织的免疫方法
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摘要
Disclosed is a composition for immunostaining of a cleared large tissue and a method of immunostaining of a cleared large living tissue using the same. The composition for immunostaining of the cleared large tissue is improved in the permeation of the antibody, which is an immunostaining problem that the conventional methods have, by improving the antibody permeability deeply in the cleared living tissue, especially in large living tissue with a thickness of 3 mm or more. By overcoming limitations and shortening the time taken for immunostaining of large tissues, it is possible to simply and quickly perform 3D bio imaging with high resolution of large living tissues, and to identify and treat the causes of various diseases through structured images It can be useful to predict the development and effectiveness and toxicity of drugs. Also. It can be used by grafting it to various medical devices, and in particular, it can be used as an in vitro diagnostic device by making it as a kit.
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