首页> 外国专利> PPP1R15A PPP1R15A A low-dose radiation-specific biomarker including a PPP1R15A gene and a PPP1R15A protein a low-dose radiation exposure diagnostic method using the biomarker and a diagnostic kit including the biomarker

PPP1R15A PPP1R15A A low-dose radiation-specific biomarker including a PPP1R15A gene and a PPP1R15A protein a low-dose radiation exposure diagnostic method using the biomarker and a diagnostic kit including the biomarker

机译:PPP1R15A PPP1R15A包括PPP1R15A基因和PPP1R15A蛋白的低剂量辐射特异性生物标志物,使用该生物标志物的低剂量辐射暴露诊断方法以及包括该生物标志物的诊断试剂盒

摘要

The present invention relates to a biomarker capable of confirming the initial cellular biological response due to low-dose radiation exposure, a diagnostic kit including the biomarker, and a method for diagnosing low-dose radiation exposure using the biomarker, comprising the PPP1R15A gene or the PPP1R15A protein. . According to the present invention as described above, by confirming the change in the expression level of new genes (PPP1R15A, SMAD6) specifically responding to exposure to low-dose radiation of 100 mSv or less, the low-dose radiation exposure of medical and radiation workers and the general public is reduced for a short time. There is an effect that can be checked within.
机译:本发明涉及一种能够确认由于低剂量辐射暴露引起的初始细胞生物学反应的生物标志物,包括该生物标志物的诊断试剂盒以及使用该生物标志物诊断低剂量辐射暴露的方法,该方法包括PPP1R15A基因或PPP1R15A蛋白。 。如上所述,根据本发明,通过确认新基因(PPP1R15A,SMAD6)的表达水平的变化,该新基因特别响应于暴露于100mSv或更低的低剂量辐射,医学和辐射的低剂量辐射暴露。工人和公众在短时间内减少。有一个可以检查的效果。

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