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Nepetalactol redox enzyme, nepetalactol synthase, and microorganisms capable of producing nepetalactone
Nepetalactol redox enzyme, nepetalactol synthase, and microorganisms capable of producing nepetalactone
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机译:荆芥内酯氧化还原酶,荆芥内酯合酶和能够产生荆芥内酯的微生物
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摘要
The present disclosure provides isolated nepetalactone redox enzyme (NOR) polypeptides, nepetalactol synthase (NEPS), and related polynucleotides, engineered host cells, and cultures, as well as methods of producing NOR and NEPS, and It provides a method of producing nepetalactol, nepetalactone, and dihydronepetalactone using these. In addition, the present disclosure provides a method for producing nepetalactone from a fermentation substrate, such as glucose, by manipulating cells (e.g., microbial cells), as well as engineered cells and related cultures having this ability, and producing nepetalactone. Provides a way.
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