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melatonin as therapeutic drug to inhibit activity of Vibrio vulnificus in vivo and in vitro infected host model

机译:褪黑素作为抑制体内和体外感染宿主模型中弧菌弧菌活性的治疗药物

摘要

The present invention relates to a composition for preventing or treating sepsis or septic shock comprising melatonin as an active ingredient. The melatonin of the present invention has the effect of inhibiting cell death of small intestinal epithelial cells infected with Vibrio bacteria, and has the effect of restoring the inhibition of mucus production of intestinal epithelial cells infected with Vibrio bacteria, thereby preventing or treating intestinal protection and sepsis. There is an effect that can be usefully used as a composition for.
机译:本发明涉及一种用于预防或治疗败血症或败血性休克的组合物,其包含褪黑激素作为有效成分。本发明的褪黑激素具有抑制被弧菌感染的小肠上皮细胞的细胞死亡的作用,并且具有恢复对被弧菌感染的肠上皮细胞的粘液产生的抑制作用的作用,从而预防或治疗肠保护和治疗。败血症。有一种效果可以有效地用作组合物。

著录项

  • 公开/公告号KR20200090513A

    专利类型

  • 公开/公告日2020-07-29

    原文格式PDF

  • 申请/专利权人 대구한의대학교산학협력단;

    申请/专利号KR20190007625

  • 发明设计人 이세중;

    申请日2019-01-21

  • 分类号A61K31/4045;A23L33/10;A61P31/04;

  • 国家 KR

  • 入库时间 2022-08-21 11:06:18

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