首页> 外国专利> CTGF Composition for diagnosing polycystic kidney disease comprising agent for detecting CTGF and use thereof

CTGF Composition for diagnosing polycystic kidney disease comprising agent for detecting CTGF and use thereof

机译:用于诊断多囊性肾病的CTGF组合物,其包含用于检测CTGF的试剂及其用途

摘要

CTGF increases expression in tissues of patients with polycystic kidneys as compared to healthy groups, and as the glomerular filtration rate decreases, the detection concentration in the patient's urine increases and can be used as a diagnostic marker for polycystic kidney disease. The present invention also includes a kit for diagnosing polycystic kidneys comprising an agent that detects CTGF, a method for providing information on the diagnosis of polycystic kidneys comprising detecting CTGF in urine, and measuring a change in CTGF concentration in a sample. Provided is a method for screening a therapeutic agent for polycystic acid.
机译:与健康组相比,CTGF增加了多囊肾患者组织中的表达,并且随着肾小球滤过率的降低,患者尿液中的检测浓度增加,可以用作多囊肾疾病的诊断标记。本发明还包括用于诊断多囊肾的试剂盒,其包含检测CTGF的试剂,提供关于诊断多囊肾的信息的方法,其包括检测尿液中的CTGF,并测量样品中CTGF浓度的变化。提供了一种筛选多囊酸治疗剂的方法。

著录项

  • 公开/公告号KR20200083344A

    专利类型

  • 公开/公告日2020-07-08

    原文格式PDF

  • 申请/专利权人 서울대학교산학협력단;

    申请/专利号KR20190176942

  • 发明设计人 안규리;김현호;

    申请日2019-12-27

  • 分类号G01N33/68;

  • 国家 KR

  • 入库时间 2022-08-21 11:06:28

相似文献

  • 专利
  • 外文文献
  • 中文文献
获取专利

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号