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Pharmaceutical composition for prevention and treatment of cancer including Glycolipid from Lipoteichoic Acid

机译:预防和治疗癌症的药物组合物,包括脂磷壁酸的糖脂

摘要

The present invention relates to an anticancer composition comprising glycolipids separated from lipoicoteic acid, which is a cell wall component of Gram-positive bacteria, and TNF-alpha and IFN-gamma as active ingredients, and the anticancer composition of the present invention is lipoteicoic acid Since the derived glycolipids, TNF-α and IFN-γ act on target cells, cancer cells specifically activate the signaling system associated with self-killing and have fewer side effects than conventional anticancer drugs, and for the active site of lipoteicoic acid By synthesizing the derivative, it not only increases the efficiency of the anti-cancer effect, but also has an excellent anti-cancer effect because cancer cells die within 24 hours.
机译:本发明涉及一种抗癌组合物,其包含与作为革兰氏阳性菌的细胞壁成分的脂解酸分离的糖脂,以及作为活性成分的TNF-α和IFN-γ,本发明的抗癌组合物为脂酸。由于衍生的糖脂,TNF-α和IFN-γ作用于靶细胞,因此癌细胞可以特异性激活与自杀有关的信号系统,并且比常规抗癌药物具有更少的副作用,并且对于脂环二十烷酸的活性位点,通过合成衍生物,不仅增加了抗癌作用的效率,而且由于癌细胞会在24小时内死亡,因此具有出色的抗癌作用。

著录项

  • 公开/公告号KR20200082724A

    专利类型

  • 公开/公告日2020-07-08

    原文格式PDF

  • 申请/专利权人 경희대학교 산학협력단;

    申请/专利号KR20180173590

  • 发明设计人 정대균;김한근;전보람;

    申请日2018-12-31

  • 分类号A61K31/7028;A61K38/19;A61K38/21;A61P35;

  • 国家 KR

  • 入库时间 2022-08-21 11:06:30

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